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多酚负载聚合物纳米治疗剂的抗癌潜力。

Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics.

机构信息

Department of Biomedical Engineering, School of Engineering, China Pharmaceutical University, Nanjing 210009, China.

Department of Medical Nanotechnology, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz 1416663547, Iran.

出版信息

Molecules. 2018 Oct 27;23(11):2787. doi: 10.3390/molecules23112787.

DOI:10.3390/molecules23112787
PMID:30373235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6278361/
Abstract

Recent evidence has extensively demonstrated the anticancer potential of nutraceuticals, including plant polyphenols. Polymeric nanocarrier systems have played an important role in improving the physicochemical and pharmacological properties of polyphenols, thus ameliorating their therapeutic effectiveness. This article summarizes the benefits and shortcomings of various polymeric systems developed for the delivery of polyphenols in cancer therapy and reveals some ideas for future work.

摘要

最近的证据广泛证明了营养保健品（包括植物多酚）的抗癌潜力。聚合物纳米载体系统在改善多酚的物理化学和药理学性质方面发挥了重要作用，从而提高了它们的治疗效果。本文总结了用于癌症治疗中多酚传递的各种聚合物系统的优点和缺点，并为未来的工作提出了一些想法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d513/6278361/b662a4cec43e/molecules-23-02787-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d513/6278361/2fe3a9df39b3/molecules-23-02787-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d513/6278361/b662a4cec43e/molecules-23-02787-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d513/6278361/2fe3a9df39b3/molecules-23-02787-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d513/6278361/b662a4cec43e/molecules-23-02787-g002.jpg

相似文献

[1]
Anti-Cancerous Potential of Polyphenol-Loaded Polymeric Nanotherapeutics.

Molecules. 2018-10-27

[2]
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[3]
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[4]
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[5]
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[6]
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[9]
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引用本文的文献

[1]
Drug Release from Nanoparticles (Polymeric Nanocapsules and Liposomes) Mimed through a Multifractal Tunnelling-Type Effect.

Polymers (Basel). 2023-2-17

[2]
Chitosan Surface-Modified PLGA Nanoparticles Loaded with Cranberry Powder Extract as a Potential Oral Delivery Platform for Targeting Colon Cancer Cells.

Pharmaceutics. 2023-2-10

[3]
Pluronics-Based Drug Delivery Systems for Flavonoids Anticancer Treatment.

Gels. 2023-2-8

[4]
Smart Vitamin Micelles as Cancer Nanomedicines for Enhanced Intracellular Delivery of Doxorubicin.

Int J Mol Sci. 2021-10-19

[5]
Catechins within the Biopolymer Matrix-Design Concepts and Bioactivity Prospects.

Antioxidants (Basel). 2020-11-26

[6]
Solid Polymeric Nanoparticles of Albendazole: Synthesis, Physico-Chemical Characterization and Biological Activity.

Molecules. 2020-11-4

[7]
Plant-Based Antidiabetic Nanoformulations: The Emerging Paradigm for Effective Therapy.

Int J Mol Sci. 2020-3-23

[8]
Dextran-Curcumin Nanoparticles as a Methotrexate Delivery Vehicle: A Step Forward in Breast Cancer Combination Therapy.

Pharmaceuticals (Basel). 2019-12-25

[9]
Nanoformulations of natural products for management of metabolic syndrome.

Int J Nanomedicine. 2019-7-16

本文引用的文献

[1]
Production of Curcumin-Loaded Silk Fibroin Nanoparticles for Cancer Therapy.

Nanomaterials (Basel). 2018-2-24

[2]
Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth.

Oncotarget. 2016-7-26

[3]
Amphiphilic Copolymeric Micelles for Doxorubicin and Curcumin Co-Delivery to Reverse Multidrug Resistance in Breast Cancer.

J Biomed Nanotechnol. 2016-5

[4]
Co-delivery of doxorubicin and curcumin by pH-sensitive prodrug nanoparticle for combination therapy of cancer.

Sci Rep. 2016-2-15

[5]
Assessing biocompatibility of graphene oxide-based nanocarriers: A review.

J Control Release. 2016-3-28

[6]
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs.

Chem Rev. 2016-3-9

[7]
Targeted intracellular protein delivery based on hyaluronic acid-green tea catechin nanogels.

Acta Biomater. 2016-3

[8]
A facile green approach to prepare core-shell hybrid PLGA nanoparticles for resveratrol delivery.

Int J Biol Macromol. 2016-3

[9]
Biological interactions of carbon-based nanomaterials: From coronation to degradation.

Nanomedicine. 2016-2

[10]
Synergistic effect of PEGylated resveratrol on delivery of anticancer drugs.

Int J Pharm. 2016-2-10

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