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亚麻籽油——作为药物和营养保健品活性成分的脂质来源。

Linseed Essential Oil - Source of Lipids as Active Ingredients for Pharmaceuticals and Nutraceuticals.

机构信息

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra (FFUC), Polo das Ciencias da Saude, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.

Biotechnology Industrial Program, Laboratory of Nanotechnology and Nanomedicine (LNMed), University of Tiradentes, Av. Murilo Dantas, 300, 49010-390 Aracaju, Sergipe, Brazil.

出版信息

Curr Med Chem. 2019;26(24):4537-4558. doi: 10.2174/0929867325666181031105603.

Abstract

Linseed - also known as flaxseed - is known for its beneficial effects on animal health attributed to its composition. Linseed comprises linoleic and α-linolenic fatty acids, various dietary fibers and lignans, which are beneficial to health because they reduce the risk of cardiovascular diseases, as well as cancer, decreasing the levels of cholesterol and relaxing the smooth muscle cells in arteries increasing the blood flow. Essential fatty acids from flax participate in several metabolic processes of the cell, not only as structuring components of the cell membrane but also as storage lipids. Flax, being considered a functional food, can be consumed in a variety of ways, including seeds, oil or flour, contributing to basic nutrition. Several formulations containing flax are available on the market in the form of e.g. capsules and microencapsulated powders having potential as nutraceuticals. This paper revises the different lipid classes found in flaxseeds and their genomics. It also discusses the beneficial effects of flax and flaxseed oil and their biological advantages as ingredients in pharmaceuticals and in nutraceuticals products.

摘要

亚麻籽,又称胡麻籽,因其成分而对动物健康具有有益的影响。亚麻籽含有亚油酸和α-亚麻酸、各种膳食纤维和木脂素,它们有益于健康,因为它们降低了心血管疾病和癌症的风险,降低了胆固醇水平,使动脉平滑肌细胞松弛,增加了血流量。亚麻中的必需脂肪酸参与细胞的几种代谢过程,不仅作为细胞膜的结构成分,而且作为储存脂质。亚麻被认为是一种功能性食品,可以通过多种方式食用,包括种子、油或面粉,为基本营养做出贡献。市场上有多种含有亚麻的配方,例如胶囊和微胶囊粉末,具有作为营养保健品的潜力。本文综述了亚麻籽中不同脂质类别的发现及其基因组学。还讨论了亚麻和亚麻籽油的有益作用,以及它们作为药物和营养保健品成分的生物学优势。

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