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[象牙海岸铜绿假单胞菌医院感染的流行病学]

[Epidemiology of Pseudomonas aeruginosa hospital infection in the Ivory Coast].

作者信息

Dosso M, Vieu J F, Wagta N, Klein B

出版信息

Bull Soc Pathol Exot Filiales. 1987;80(1):19-27.

PMID:3038353
Abstract

210 P. aeruginosa hospital strains isolated at Abidjan from pathological samples or contaminated material were studied by means of serotyping, biotyping, phage-typing and for their resistance to eleven antibiotics. 87% were classified into 14 serogroups: O:1, O:2, O:3, O:4, O:5, O:6, O:8, O:9, O:10, O:11, O:12, O:13, O:15, O:16. No strains were O:7 or O:14. The presence of an ortho-nitrophenyl beta-d-galactopyranoside hydrolase was demonstrated in 42 strains belonging to the serogroup O:11. Sixty-five phage-types were defined but 37% of strains were untypable by phages. The incidence of resistance to each tested antibiotic was as follows: carbenicillin 49%, mezlocillin 44%, ticarcillin 34%, azlocillin 25%, cefamandole 94%, latamoxef 15%, cefotaxime 41%, cefsulodin 32%, tobramycin 35%, amikacin 7%, gentamicin 39%. Thirty-eight strains were multiresistant to carbenicillin, mezlocillin, ticarcillin, azlocillin, and four strains to eleven antibiotics. These results are compared with data of the scientific literature on the epidemiology of hospital Pseudomonas infection.

摘要

对在阿比让从病理样本或受污染材料中分离出的210株铜绿假单胞菌医院菌株进行了血清分型、生物分型、噬菌体分型研究,并检测了它们对11种抗生素的耐药性。87%的菌株被分为14个血清群:O:1、O:2、O:3、O:4、O:5、O:6、O:8、O:9、O:10、O:11、O:12、O:13、O:15、O:16。没有O:7或O:14血清群的菌株。在属于O:11血清群的42株菌株中证实存在邻硝基苯基β-D-吡喃半乳糖苷水解酶。确定了65种噬菌体类型,但37%的菌株无法用噬菌体分型。对每种测试抗生素的耐药发生率如下:羧苄西林49%、美洛西林44%、替卡西林34%、阿洛西林25%、头孢孟多94%、拉氧头孢15%、头孢噻肟41%、头孢磺啶32%、妥布霉素35%、阿米卡星7%、庆大霉素39%。38株菌株对羧苄西林、美洛西林、替卡西林、阿洛西林多重耐药,4株菌株对11种抗生素耐药。将这些结果与关于医院假单胞菌感染流行病学的科学文献数据进行了比较。

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