García-Rosales Francisco, Martin Lisa M, Beetz M Jerome, Cabral-Calderin Yuranny, Kössl Manfred, Hechavarria Julio C
Institut für Zellbiologie und Neurowissenschaft, Goethe-Universität, Max-von-Laue-Str. 13, 60438 Frankfurt am Main, Germany.
Institut für Zellbiologie und Neurowissenschaft, Goethe-Universität, Max-von-Laue-Str. 13, 60438 Frankfurt am Main, Germany.
iScience. 2018 Nov 30;9:47-62. doi: 10.1016/j.isci.2018.10.009. Epub 2018 Oct 16.
The extraction of temporal information from sensory input streams is of paramount importance in the auditory system. In this study, amplitude-modulated sounds were used as stimuli to drive auditory cortex (AC) neurons of the bat species Carollia perspicillata, to assess the interactions between cortical spikes and local-field potentials (LFPs) for the processing of temporal acoustic cues. We observed that neurons in the AC capable of eliciting synchronized spiking to periodic acoustic envelopes were significantly more coherent to theta- and alpha-band LFPs than their non-synchronized counterparts. These differences occurred independently of the modulation rate tested and could not be explained by power or phase modulations of the field potentials. We argue that the coupling between neuronal spiking and the phase of low-frequency LFPs might be important for orchestrating the coding of temporal acoustic structures in the AC.
从感觉输入流中提取时间信息在听觉系统中至关重要。在本研究中，使用调幅声音作为刺激来驱动食果蝠（Carollia perspicillata）的听觉皮层（AC）神经元，以评估皮层尖峰与局部场电位（LFP）之间在处理时间声学线索方面的相互作用。我们观察到，与非同步的对应神经元相比，能够对周期性声包络产生同步尖峰的AC神经元与θ波和α波段LFP的相关性显著更高。这些差异独立于所测试的调制率出现，并且不能用场电位的功率或相位调制来解释。我们认为，神经元尖峰与低频LFP相位之间的耦合可能对于协调AC中时间声学结构的编码很重要。
