García-Rosales Francisco, Beetz M Jerome, Cabral-Calderin Yuranny, Kössl Manfred, Hechavarria Julio C
Institut für Zellbiologie und Neurowissenschaft, Goethe-Universität, 60438, Frankfurt/M., Germany.
Department of Zoology II, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
Commun Biol. 2018 Nov 20;1:200. doi: 10.1038/s42003-018-0205-5. eCollection 2018.
Experimental evidence supports that cortical oscillations represent multiscale temporal modulations existent in natural stimuli, yet little is known about the processing of these multiple timescales at a neuronal level. Here, using extracellular recordings from the auditory cortex (AC) of awake bats (), we show the existence of three neuronal types which represent different levels of the temporal structure of conspecific vocalizations, and therefore constitute direct evidence of multiscale temporal processing of naturalistic stimuli by neurons in the AC. These neuronal subpopulations synchronize differently to local-field potentials, particularly in theta- and high frequency bands, and are informative to a different degree in terms of their spike rate. Interestingly, we also observed that both low and high frequency cortical oscillations can be highly informative about the listened calls. Our results suggest that multiscale neuronal processing allows for the precise and non-redundant representation of natural vocalizations in the AC.
实验证据支持皮层振荡代表自然刺激中存在的多尺度时间调制，但在神经元水平上对这些多个时间尺度的处理知之甚少。在这里，通过对清醒蝙蝠听觉皮层（AC）进行细胞外记录，我们发现存在三种神经元类型，它们代表同种发声时间结构的不同水平，因此构成了AC中神经元对自然主义刺激进行多尺度时间处理的直接证据。这些神经元亚群与局部场电位的同步方式不同，特别是在θ和高频波段，并且在放电率方面具有不同程度的信息性。有趣的是，我们还观察到低频和高频皮层振荡都可以提供关于所听到叫声的高度信息。我们的结果表明，多尺度神经元处理允许在AC中对自然发声进行精确且非冗余的表征。
