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慢性缺血性二尖瓣反流与外科治疗前景

Chronic ischemic mitral valve regurgitation and surgical perspectives.

作者信息

Altarabsheh Salah Eldien, Deo Salil V, Rababa'h Abeer, Obeidat Yagthan M, Haddad Osama

机构信息

Division of Cardiovascular Surgery, Queen Alia Heart Institute, Amman 11953, Jordan.

Division of Cardiovascular Surgery, Harrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, OH 44106, United States.

出版信息

World J Cardiol. 2018 Oct 26;10(10):141-144. doi: 10.4330/wjc.v10.i10.141.

Abstract

Chronic ischemic mitral valve regurgitation is a result of disturbed left ventricular geometry secondary to myocardial ischemia in the absence of intrinsic mitral valve pathology. It is a common complication after myocardial infarction, and patients who have ischemic mitral regurgitation (IMR) have a worse prognosis compared to patients who have ischemic heart disease alone, and this is directly related to the severity of IMR. Medical therapy has limited efficacy, and surgical options including various repair techniques and valve replacement had been tried with variable success. Still there is intense debate among surgeons whether to interfere with moderate degree IMR at the time of coronary artery revascularization.

摘要

慢性缺血性二尖瓣反流是在没有二尖瓣内在病变的情况下,继发于心肌缺血的左心室几何形状紊乱的结果。它是心肌梗死后的常见并发症,与仅患有缺血性心脏病的患者相比,患有缺血性二尖瓣反流(IMR)的患者预后更差,这与IMR的严重程度直接相关。药物治疗效果有限,包括各种修复技术和瓣膜置换在内的手术选择也已尝试,但成功率各不相同。对于在冠状动脉血运重建时是否干预中度IMR,外科医生之间仍存在激烈争论。

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Surgical treatment of moderate ischemic mitral regurgitation.中度缺血性二尖瓣反流的外科治疗
N Engl J Med. 2014 Dec 4;371(23):2178-88. doi: 10.1056/NEJMoa1410490. Epub 2014 Nov 18.
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Ischemic mitral regurgitation.缺血性二尖瓣反流。
Circ J. 2013;77(8):1952-6. doi: 10.1253/circj.cj-13-0743. Epub 2013 Jul 19.

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