Alsmman Alahmady Hamad, Mostafa Engy Mohamed, Mounir Amr
Sohag Faculty of Medicine, Ophthalmology Department, Sohag, Egypt.
Med Hypothesis Discov Innov Ophthalmol. 2018 Fall;7(3):126-132.
This study was designed to evaluate the efficacy of low-dose of oral acetylsalicylic acid (aspirin) with focal argon laser for the treatment of acute central serous chorioretinopathy (CSCR). In this prospective case-control study, 40 Patients with acute CSCR were classified randomly to two groups; group A with no treatment as the control group and group B with argon Laser in focal treatment once, followed by aspirin, 100 mg per day orally, with follow up period of 12 months by evaluation of visual acuity, and by Optical Coherence Tomography (OCT), every three months for one year. Patients in the second group treated with argon Laser and aspirin showed more clinically significant improvement in both visual acuity and OCT macular thickness by the end of the follow-up period when compared with the observational group. It was concluded that argon Laser with low-dose oral aspirin results in improvement of visual acuity and OCT macular thickness.
本研究旨在评估低剂量口服乙酰水杨酸(阿司匹林)联合局部氩激光治疗急性中心性浆液性脉络膜视网膜病变(CSCR)的疗效。在这项前瞻性病例对照研究中,40例急性CSCR患者被随机分为两组;A组不进行治疗作为对照组,B组进行一次局部氩激光治疗,随后口服阿司匹林,每日100毫克,随访12个月,通过评估视力以及每三个月进行一次光学相干断层扫描(OCT),持续一年。与观察组相比,接受氩激光和阿司匹林治疗的第二组患者在随访期末视力和OCT黄斑厚度方面均有更显著的临床改善。研究得出结论,氩激光联合低剂量口服阿司匹林可改善视力和OCT黄斑厚度。