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身体功能变化作为短期死亡率预测指标。

Changes in Physical Functioning as Short-Term Predictors of Mortality.

机构信息

Office of Population Research, Princeton University, New Jersey.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2020 Feb 14;75(3):630-639. doi: 10.1093/geronb/gby133.

DOI:10.1093/geronb/gby133
PMID:30388248
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7768692/
Abstract

OBJECTIVES

Both performance-based and self-reported measures of physical functioning are predictors of mortality. There has been relatively little research examining whether their changes predict mortality. This study examines whether 5-year changes in performance-based and self-reported measures of functioning predict subsequent mortality.

METHOD

Data are from the 2006 wave of the Social Environment and Biomarkers of Aging Study, 2011 wave of the Taiwan Longitudinal Study of Aging, and mortality follow-up through 2015. Gompertz proportional hazard models predict mortality from changes in ability to complete performance-based tests and changes in performance-based and self-reported functioning.

RESULTS

Incident inability to complete at least one performance-based test of functioning is associated with twice the risk of subsequent 4-year mortality. Conditional on the baseline measurement, a one standard deviation (SD) decline in grip strength is associated with a 61% increased risk of 4-year mortality; a one-SD decline in walking speed and a one-SD increase in self-reported limitations are both associated with around a 40% increased risk of 4-year mortality. Conditional on the most recent measurement of functioning, prior change is not significantly associated with subsequent mortality.

DISCUSSION

Repeated measures of performance-based and self-reported functioning are valuable in that they provide an updated measurement of functioning.

摘要

目的

基于表现的和自我报告的身体功能测量都是死亡率的预测指标。相对较少的研究检验了它们的变化是否可以预测死亡率。本研究检验了基于表现的和自我报告的功能测量的 5 年变化是否可以预测随后的死亡率。

方法

数据来自 2006 年社会环境与衰老生物标志物研究的波次、2011 年台湾老龄化纵向研究的波次,以及截至 2015 年的死亡率随访。戈珀特比例风险模型预测了从基于表现的测试能力变化和基于表现的和自我报告的功能变化中预测死亡率。

结果

新出现的无法完成至少一项基于表现的功能测试与随后 4 年死亡率增加两倍有关。在基线测量的基础上,握力下降一个标准差与 4 年死亡率增加 61%有关;步行速度下降一个标准差和自我报告的限制增加一个标准差都与 4 年死亡率增加约 40%有关。在最近的功能测量的基础上,先前的变化与随后的死亡率没有显著关联。

讨论

基于表现的和自我报告的功能的重复测量是有价值的,因为它们提供了功能的更新测量。

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本文引用的文献

1
flexsurv: A Platform for Parametric Survival Modeling in R.flexsurv:R语言中用于参数生存建模的一个平台。
J Stat Softw. 2016 May 12;70. doi: 10.18637/jss.v070.i08.
2
Physical Function in U.S. Older Adults Compared With Other Populations: A Multinational Study.美国老年人与其他人群的身体机能比较:一项多国研究。
J Aging Health. 2019 Aug;31(7):1067-1084. doi: 10.1177/0898264318759378. Epub 2018 Feb 22.
3
"Taking a Turn for the Better": Does Self-reported Recovery From Walking Limitation Improve Disability and Mortality Outcomes?“好转的转机”:自我报告的行走受限恢复是否能改善残疾和死亡率结局?
J Gerontol B Psychol Sci Soc Sci. 2018 Sep 20;73(7):1278-1291. doi: 10.1093/geronb/gbw113.
4
Relative Handgrip Strength Is a Simple Indicator of Cardiometabolic Risk among Middle-Aged and Older People: A Nationwide Population-Based Study in Taiwan.相对握力是中老年人心血管代谢风险的一个简单指标:一项基于台湾全国人口的研究
PLoS One. 2016 Aug 25;11(8):e0160876. doi: 10.1371/journal.pone.0160876. eCollection 2016.
5
Three year functional changes and long-term mortality hazard in community-dwelling older men.社区居住的老年男性三年内的功能变化和长期死亡危险。
Eur J Intern Med. 2016 Nov;35:66-72. doi: 10.1016/j.ejim.2016.06.006. Epub 2016 Jul 2.
6
I forgot when I lost my grip-strong associations between cognition and grip strength in level of performance and change across time in relation to impending death.我忘记了自己何时失去握力——认知与握力在表现水平以及与濒死相关的随时间变化方面存在紧密关联。
Neurobiol Aging. 2016 Feb;38:68-72. doi: 10.1016/j.neurobiolaging.2015.11.010. Epub 2015 Nov 24.
7
Associations of Walking Speed, Grip Strength, and Standing Balance With Total and Cause-Specific Mortality in a General Population of Japanese Elders.在日本老年人的一般人群中,行走速度、握力和站立平衡与总死亡率和特定原因死亡率的关系。
J Am Med Dir Assoc. 2016 Feb;17(2):184.e1-7. doi: 10.1016/j.jamda.2015.11.003. Epub 2015 Dec 21.
8
Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study.握力的预后价值:来自前瞻性城乡流行病学(PURE)研究的结果。
Lancet. 2015 Jul 18;386(9990):266-73. doi: 10.1016/S0140-6736(14)62000-6. Epub 2015 May 13.
9
Performance-based measures of physical function as mortality predictors: Incremental value beyond self-reports.基于表现的身体功能测量作为死亡率预测指标:超越自我报告的增量价值。
Demogr Res. 2014 Jan 23;30(7):227-252. doi: 10.4054/DemRes.2013.30.7.
10
Cohort Profile: The Social Environment and Biomarkers of Aging Study (SEBAS) in Taiwan.队列简介:台湾社会环境与衰老生物标志物研究(SEBAS)
Int J Epidemiol. 2016 Feb;45(1):54-63. doi: 10.1093/ije/dyu179. Epub 2014 Sep 8.