Lee Wei-Ju, Peng Li-Ning, Chiou Shu-Ti, Chen Liang-Kung
Aging and Health Research Center, National Yang Ming University, Taipei City, Taiwan.
Institute of Public Health, National Yang Ming University, Taipei City, Taiwan.
PLoS One. 2016 Aug 25;11(8):e0160876. doi: 10.1371/journal.pone.0160876. eCollection 2016.
Muscle strength may play an important role in cardiovascular health. The study was intended to evaluate the association between cardiometabolic risk, risk of coronary artery disease and handgrip strength by using the relative handgrip strength.
Data of 927 Taiwanese aged 53 years and older (510 men and 417 women) were retrieved from a nationwide representative population-based cohort cross-sectional study in 2006. All participants were interviewed face-to-face and received measures of anthropometry, dominant handgrip strength, relative handgrip strength (summation of both handgrip strength divided by body mass index) and serum biomarkers.
Multivariate linear regression analysis showed the significant association between relative handgrip strength and favorable cardiometabolic risk factors including blood pressure, triglyceride, total cholesterol to high density cholesterol(HDL-C) ratio, glycohemoglobin (HbA1c), uric acid, Framingham risk score in men, and HDL-C, fasting glucose, HbA1c, log hsCRP in women. Dominant hand grip strength was only associated with log hsCRP in women. (p<0.05 for all), but was not significant associated with all cardiovascular biomarkers and FRS in both sex.
Joint with handgrip strength and body size, as relative handgrip strength, may be a better tool to capture conceptual concomitant health, which may be a simple, inexpensive, and easy-to-use tool when targeting cardiovascular health in public health level.
肌肉力量可能在心血管健康中发挥重要作用。本研究旨在通过使用相对握力来评估心脏代谢风险、冠状动脉疾病风险与握力之间的关联。
从2006年一项全国代表性的基于人群的队列横断面研究中获取了927名53岁及以上台湾人的数据(510名男性和417名女性)。所有参与者均接受了面对面访谈,并接受了人体测量、优势手握力、相对握力(双手握力总和除以体重指数)和血清生物标志物的测量。
多变量线性回归分析显示,相对握力与有利的心脏代谢风险因素之间存在显著关联,这些因素包括血压、甘油三酯、总胆固醇与高密度脂蛋白胆固醇(HDL-C)比值、糖化血红蛋白(HbA1c)、尿酸、男性的弗雷明汉风险评分,以及女性的HDL-C、空腹血糖、HbA1c、高敏C反应蛋白(hsCRP)对数。优势手握力仅与女性的hsCRP对数相关(所有p<0.05),但与两性的所有心血管生物标志物和弗雷明汉风险评分均无显著关联。
结合握力和体型的相对握力可能是一种更好的衡量整体健康状况的工具,在公共卫生层面针对心血管健康时,它可能是一种简单、廉价且易于使用的工具。