用未加工麸皮进行维持治疗预防急性肛裂复发。
Maintenance therapy with unprocessed bran in the prevention of acute anal fissure recurrence.
作者信息
Jensen S L
出版信息
J R Soc Med. 1987 May;80(5):296-8. doi: 10.1177/014107688708000513.
The effect of unprocessed bran in a dose of 5 g three times daily and a dose of 2.5 g three times daily for one year on the recurrence rate of anal fissures was studied in a double-blind, placebo-controlled trial in 90 patients with recently healed acute posterior anal fissures. Fifteen patients (16.6%) were withdrawn before the code was broken due to failure to follow the trial protocol for various reasons. Significantly fewer recurrences occurred in patients receiving bran 5 g three times daily (recurrence rate 16%, 95% confidence limits, 4.54 to 36.08) when compared with patients receiving bran 2.5 g three times daily (60%; 38.67 to 78.87) (P less than 0.01) and with patients receiving placebo three times daily (68%; 46.50 to 85.05) (P less than 0.01). No significant difference in recurrences was found between patients on bran 2.5 g and those on placebo.
在一项针对90例近期愈合的急性后位肛裂患者的双盲、安慰剂对照试验中，研究了每日三次服用5克未加工麸皮和每日三次服用2.5克未加工麸皮，持续一年对肛裂复发率的影响。15名患者（16.6%）因各种原因未遵循试验方案，在揭盲前退出。与每日三次服用2.5克麸皮的患者（60%；38.67至78.87）（P<0.01）以及每日三次服用安慰剂的患者（68%；46.50至85.05）（P<0.01）相比，每日三次服用5克麸皮的患者复发率显著更低（复发率16%，95%置信区间，4.54至36.08）。每日服用2.5克麸皮的患者与服用安慰剂的患者在复发率上无显著差异。
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