一种制备光学活性1-氨基茚满-2-醇的便捷酶促路线：用于HIV-1蛋白酶抑制剂和不对称合成的多功能配体。
A Convenient Enzymatic Route to Optically Active l-Aminoindan-2-ol: Versatile Ligands for HIV-1 Protease Inhibitors and Asymmetric Syntheses.
作者信息
Ghosh Arun K, Kincaid John F, Haske Michael G
机构信息
Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, USA.
出版信息
Synthesis (Stuttg). 1997 May;1997(5):541-544. doi: 10.1055/s-1997-1235.
Abstract
(1,2)- and (1,2)-l-aminoindan-2-ol were prepared in high enantiomeric excess (>96%) by an immobilized lipase-catalyzed selective acylation of racemic - l-azidoindan-2-ol.
摘要
通过固定化脂肪酶催化外消旋-1-叠氮茚满-2-醇的选择性酰化反应，以高对映体过量（>96%）制备了(1,2)-和(1,2)-l-氨基茚满-2-醇。
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