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Mendelian Randomization in Case Only Studies: A Promising Approach to be Applied With Caution.

作者信息

Mitchell Ruth E, Paternoster Lavinia, Davey Smith George

机构信息

MRC Intergrative Epidemiology Unit, University of Bristol, United Kingdom.

MRC Intergrative Epidemiology Unit, University of Bristol, United Kingdom.

出版信息

Am J Cardiol. 2018 Dec 15;122(12):2169-2171. doi: 10.1016/j.amjcard.2018.09.035. Epub 2018 Sep 28.

DOI:10.1016/j.amjcard.2018.09.035
PMID:30396509
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6286634/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9a1/6286634/88ca799a62cf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9a1/6286634/88ca799a62cf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9a1/6286634/88ca799a62cf/gr1.jpg

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本文引用的文献

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Obesity (Silver Spring). 2018 Nov;26(11):1796-1806. doi: 10.1002/oby.22313.
2
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3
Influence of Body Mass Index on Long-Term Survival After Cardiac Catheterization.体重指数对心脏导管插入术后长期生存的影响。
应用孟德尔随机化评估营养与癌症之间关系的因果关系。
Cancer Causes Control. 2022 May;33(5):631-652. doi: 10.1007/s10552-022-01562-1. Epub 2022 Mar 11.
4
A framework for transcriptome-wide association studies in breast cancer in diverse study populations.用于在不同研究人群的乳腺癌中转录组全基因组关联研究的框架。
Genome Biol. 2020 Feb 20;21(1):42. doi: 10.1186/s13059-020-1942-6.
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Using Openly Accessible Resources to Strengthen Causal Inference in Epigenetic Epidemiology of Neurodevelopment and Mental Health.利用公开可获取的资源加强神经发育和精神健康表观遗传学的因果推断。
Genes (Basel). 2019 Mar 1;10(3):193. doi: 10.3390/genes10030193.
Am J Cardiol. 2018 Jan 1;121(1):113-119. doi: 10.1016/j.amjcard.2017.09.028. Epub 2017 Oct 13.
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Collider scope: when selection bias can substantially influence observed associations.碰撞范围：当选择偏差可能对观察到的关联产生实质性影响时。
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