Department of Preventive Medicine, University of Southern California, Los Angeles, California; and
Department of Psychiatry, School of Medicine, Yale University, New Haven, Connecticut.
Pediatrics. 2018 Dec;142(6). doi: 10.1542/peds.2018-0486. Epub 2018 Nov 5.
: media-1vid110.1542/5839992666001PEDS-VA_2018-0486 BACKGROUND AND OBJECTIVES: Electronic cigarette (e-cigarette) use is associated with cigarette initiation among adolescents. However, it is unclear whether e-cigarette use is associated with more frequent cigarette use after initiation. Also, the extent to which cigarette or dual cigarette and e-cigarette users transition to exclusive e-cigarette use or to the nonuse of either product is not yet known.
Data were pooled from 3 prospective cohort studies in California and Connecticut (baseline: 2013-2014; follow-up: 2014-2016; = 6258). Polytomous regression models were used to evaluate the association of baseline e-cigarette use (never or ever) with cigarette use frequency at follow-up (experimental: initiation but no past-30-day use; infrequent: 1-2 of the past 30 days; frequent: 3-5 or more of the past 30 days). Polytomous regression models were also used to evaluate transitions between baseline ever or past-30-day single or dual product use and past-30-day single or dual product use at follow-up.
Among baseline never smokers, e-cigarette users had greater odds of subsequent experimental (odds ratio [OR] = 4.58; 95% confidence interval [CI]: 3.56-5.88), infrequent (OR = 4.27; 95% CI: 2.75-6.62) or frequent (OR = 3.51; 95% CI: 1.97-6.24) cigarette use; the 3 OR estimates were not significantly different. Baseline past-30-day exclusive cigarette use was associated with higher odds at follow-up of exclusive cigarette or dual product use than of exclusive e-cigarette use.
Tobacco control policy to reduce adolescent use of both e-cigarettes and cigarettes is needed to prevent progression to more frequent tobacco use patterns and reduce combustible cigarette use (with or without concurrent e-cigarette use) to lessen the adverse public health impact of e-cigarettes.
电子烟的使用与青少年开始吸烟有关。但是,电子烟的使用是否与起始后更频繁地吸烟有关尚不清楚。此外,尚不清楚有多少香烟或香烟和电子烟的双重使用者过渡到只使用电子烟或不再使用任何一种产品。
数据来自加利福尼亚州和康涅狄格州的 3 项前瞻性队列研究(基线:2013-2014 年;随访:2014-2016 年;n=6258)。多变量回归模型用于评估基线电子烟使用(从未或曾经)与随访时香烟使用频率之间的关联(实验性:起始但过去 30 天无使用;不频繁:过去 30 天 1-2 天;频繁:过去 30 天 3-5 天或更多天)。多变量回归模型还用于评估基线曾经或过去 30 天单一或双重产品使用与随访时过去 30 天单一或双重产品使用之间的转换。
在基线从不吸烟者中,电子烟使用者随后发生实验性吸烟(比值比[OR] = 4.58;95%置信区间[CI]:3.56-5.88)、不频繁(OR = 4.27;95% CI:2.75-6.62)或频繁(OR = 3.51;95% CI:1.97-6.24)吸烟的可能性更高;3 个 OR 估计值无显著差异。基线过去 30 天的独家香烟使用与随访时独家香烟或双重产品使用的可能性更高相关,而不是独家电子烟使用。
需要制定烟草控制政策以减少青少年对电子烟和香烟的使用,以防止向更频繁的烟草使用模式发展,并减少可燃香烟的使用(无论是否同时使用电子烟),以减轻电子烟对公共健康的不利影响。