Center for Alcohol and Addiction Studies, Brown University, Providence, RI.
Nicotine Tob Res. 2020 Dec 15;22(Suppl 1):S54-S60. doi: 10.1093/ntr/ntaa150.
Exclusive e-cigarette use has been shown to be associated with reduced levels of respiratory symptoms relative to smoking combustible cigarettes; this association has been less frequently studied in smokers using advanced-generation e-cigarette devices. Advanced-generation devices generate denser vapor than either early generation or pod-style devices, and engender longer inhalations; these vaping topography patterns may contribute to respiratory symptoms.
In a single-session, cross-sectional study of exclusive e-cigarette users (N = 59) and dual users of e-cigarettes and cigarettes (N = 54), participants completed questionnaires, including the American Thoracic Society Questionnaire (ATSQ) and were videotaped vaping their own device in the lab for 1 hour. Using a hierarchical regression method, we examined whether topography variables, level of nicotine concentration used in their e-cigarette device in the past month, e-cigarette dependence, amount of e-cigarette use in the past month, and smoking status (any smoking in the last month vs. none) predicted ATSQ score severity.
There was a significant mean difference in ATSQ score across smoking status, with greater ATSQ scores for vapers who also smoked cigarettes (19.0, SD = 6.7) than for exclusive vapers (13.4, SD = 5.3). In the final model, of the predictors of interest, only cigarette smoking status predicted significantly greater ATSQ scores (overall F = 2.51, p = .006; R2 = .26; smoking status β = 0.39, p < .0001).
Findings suggest that differences in respiratory symptoms between dual and exclusive e-cigarette users appear to be attributable to combustible cigarette smoking, rather than more intense or frequent e-cigarette use across groups.
In this comparison of exclusive advanced-generation vape device users (N = 59) versus dual users of these devices and combustible cigarettes (N = 54), we set out to determine the extent to which smoking status and e-cigarette use variables predicted self-reported respiratory symptom severity. We found that dual users showed greater respiratory symptom severity (ATSQ scores) than exclusive vapers. Despite examining vaping topography and other variables, smoking status and race were the only significant predictor of respiratory symptoms. We conclude that combustible cigarette use, not individual vaping topography, likely accounts for differences in respiratory symptoms between dual users and exclusive vapers.
与吸可燃香烟相比，使用电子烟可降低呼吸道症状的水平。然而，这种关联在使用新一代电子烟设备的吸烟者中研究较少。与早期或烟弹式设备相比，新一代设备产生的烟雾更浓，吸入时间更长；这些吸电子烟的模式可能会导致呼吸道症状。
在一项针对单一疗程、横断面的电子烟使用者（N=59）和电子烟与香烟双重使用者（N=54）的研究中，参与者完成了问卷调查，包括美国胸科学会问卷（ATSQ），并在实验室中使用自己的设备进行了 1 小时的吸电子烟录像。我们使用分层回归方法，检验了吸电子烟模式变量、过去一个月中使用的电子烟尼古丁浓度水平、电子烟依赖程度、过去一个月中电子烟的使用量以及吸烟状况（过去一个月中是否吸烟）是否能预测 ATSQ 评分的严重程度。
吸烟状况在 ATSQ 评分上有显著的平均差异，与仅吸电子烟的人（19.0，SD=6.7）相比，同时吸电子烟和香烟的人（21.7，SD=6.7）的 ATSQ 评分更高。在最终模型中，在感兴趣的预测因素中，只有吸烟状况显著预测更高的 ATSQ 评分（总体 F=2.51，p=0.006；R2=0.26；吸烟状况β=0.39，p<0.0001）。
研究结果表明，双重电子烟使用者和单一电子烟使用者之间呼吸道症状的差异似乎归因于可燃香烟的使用，而不是两组之间更强烈或更频繁的电子烟使用。
在这项对 59 名仅使用先进一代电子烟设备的使用者（N=59）与同时使用这些设备和可燃香烟的双重使用者（N=54）的比较中，我们旨在确定吸烟状况和电子烟使用变量在多大程度上预测自我报告的呼吸道症状严重程度。我们发现，双重使用者的呼吸道症状严重程度（ATSQ 评分）高于仅吸电子烟者。尽管我们检查了吸电子烟的模式和其他变量，但吸烟状况和种族是唯一能显著预测呼吸道症状的因素。我们得出的结论是，可燃香烟的使用而不是个人吸电子烟的模式，可能解释了双重使用者和单一吸电子烟者之间呼吸道症状的差异。
