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病例报告:狂犬病存活病例:来自印度的病例系列。

Case Reports: Survival from Rabies: Case Series from India.

机构信息

Department of Neurovirology, WHO Collaborating Centre for Reference and Research in Rabies, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.

Department of Infectious Diseases, MGM New Bombay Hospital, Mumbai, India.

出版信息

Am J Trop Med Hyg. 2019 Jan;100(1):165-169. doi: 10.4269/ajtmh.18-0711.

Abstract

Rabies, a zoonotic viral encephalitis, continues to be a serious public health problem in India and several other countries in Asia and Africa. Survival is rarely reported in rabies, which is considered to be almost universally fatal. We report the clinical and radiological findings of eight patients with laboratory-confirmed rabies who survived the illness. With the exception of one patient who recovered with mild sequelae, all survivors had poor functional outcomes. The reported survival from rabies in recent years may reflect an increased awareness of the disease and greater access to better critical care facilities in rabies-endemic countries. Nonetheless, there is an urgent need to focus on preventive strategies to reduce the burden of this dreadful disease in rabies-endemic countries.

摘要

狂犬病是一种动物源性病毒性脑炎,在印度和亚洲、非洲的其他几个国家仍然是一个严重的公共卫生问题。狂犬病几乎被认为是普遍致命的,很少有存活的报道。我们报告了 8 例实验室确诊狂犬病患者的临床和影像学发现,他们幸存了下来。除了 1 例患者有轻微后遗症恢复外,所有幸存者的功能预后都较差。近年来报告的狂犬病存活病例可能反映出对该病的认识提高了,以及在狂犬病流行国家更容易获得更好的重症监护设施。尽管如此,仍迫切需要关注预防策略,以减轻狂犬病流行国家这种可怕疾病的负担。

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本文引用的文献

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Rabies.狂犬病。
Nat Rev Dis Primers. 2017 Nov 30;3:17091. doi: 10.1038/nrdp.2017.91.
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Human Rabies Survivors in India: An Emerging Paradox?印度的人类狂犬病幸存者:一个新出现的悖论?
PLoS Negl Trop Dis. 2016 Jul 28;10(7):e0004774. doi: 10.1371/journal.pntd.0004774. eCollection 2016 Jul.
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Rabies: Rare Human Infection - Common Questions.狂犬病:罕见的人类感染——常见问题
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Antemortem diagnosis and prevention of human rabies.人类狂犬病的生前诊断与预防
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