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老挝犬类狂犬病疫苗接种情况:犬主知识及犬类血清学状况

Rabies Vaccination in Dogs in Laos: Owner Knowledge and Serological Status of Dogs.

作者信息

Velander Lovisa, Fogelberg Johanna, Putthana Vannaphone, Keosengthong Amphone, Lindahl Johanna Frida

机构信息

Department of Clinical Sciences, Swedish University of Agricultural Sciences, 75007 Uppsala, Sweden.

Department of Veterinary Medicine, Faculty of Agriculture, Nabong Campus, National University of Laos, Vientiane 0100, Laos.

出版信息

Pathogens. 2022 Jan 6;11(1):69. doi: 10.3390/pathogens11010069.

Abstract

Rabies is an infectious disease which is virtually 100% fatal. Humans are most often infected through the bite of an infected dog, and most cases could be prevented by vaccinating dogs. However, vaccination coverage is insufficient in most countries where canine rabies occurs endemically. This study conducted interviews and sampling of dogs in Laos to understand more about the barriers for vaccination and to evaluate the antibody status of dogs using a commercial ELISA. The study found that only 62% out of 359 dog owners knew what rabies was, and only 24% knew the disease could be fatal. Higher education was associated with higher knowledge scores. Only 56 out of 437 (13%) dogs had been rabies vaccinated according to their owner, and out of these dogs, only 34 (61%) had antibodies, and only 48% had adequate levels (above 0.5 IU/mL). However, 24% of the dogs with no known history of vaccination had antibodies, indicating either exposure or vaccination in the past without the owner's awareness. In conclusion, this study indicates that there is a low level of knowledge about rabies, and that owner knowledge is not a good indicator of whether a dog is vaccinated or not.

摘要

狂犬病是一种几乎100%致命的传染病。人类最常通过感染狂犬病的狗的咬伤而感染,并且大多数病例可以通过给狗接种疫苗来预防。然而,在大多数犬类狂犬病地方性流行的国家,疫苗接种覆盖率不足。本研究在老挝对狗进行了访谈和采样,以更多地了解疫苗接种的障碍,并使用商业酶联免疫吸附测定法评估狗的抗体状态。研究发现,在359名狗主人中,只有62%知道什么是狂犬病,只有24%知道这种疾病可能致命。受教育程度越高,知识得分越高。据主人称,在437只狗中只有56只(13%)接种过狂犬病疫苗,在这些狗中,只有34只(61%)有抗体,只有48%的狗抗体水平足够(高于0.5国际单位/毫升)。然而,24%无已知疫苗接种史的狗有抗体,这表明它们要么过去接触过病毒,要么在主人不知情的情况下接种过疫苗。总之,本研究表明人们对狂犬病的了解程度较低,而且主人的知识水平并不能很好地表明狗是否接种过疫苗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f086/8778959/072b5c37c5e6/pathogens-11-00069-g001.jpg

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