评估主要医学期刊中先前发表的随机临床试验将统计显著性的 P 值阈值从 0.05 降低至 0.005 的效果。
Evaluation of Lowering the P Value Threshold for Statistical Significance From .05 to .005 in Previously Published Randomized Clinical Trials in Major Medical Journals.
机构信息
Oklahoma State University Center for Health Sciences, Tulsa.
出版信息
JAMA. 2018 Nov 6;320(17):1813-1815. doi: 10.1001/jama.2018.12288.
Abstract
This study evaluates primary end points in randomized clinical trials (RCTs) published in 3 major general medical journals to determine how changing the value threshold for statistical significance from .05 to .005 could affect the interpretation of previously published RCTs.
摘要
本研究评估了发表在三大普通医学期刊上的随机临床试验（RCT）的主要终点，以确定将统计显著性的阈值从 0.05 更改为 0.005 会如何影响对先前发表的 RCT 的解释。
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