Chindaprasirt Prin, Promsorn Julaluck, Ungareewittaya Piti, Twinprai Nattaphon, Chindaprasirt Jarin
Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Mol Clin Oncol. 2018 Nov;9(5):532-534. doi: 10.3892/mco.2018.1720. Epub 2018 Sep 17.
Cholangiocarcinoma is an aggressive tumor of the hepatic biliary system and it commonly spreads to the regional lymph nodes, liver and lungs. However, bone metastasis from cholangiocarcinoma is rare compared with other tumors. We herein present the case of a 61-year-old Asian woman who presented with pain in the right scapular area. Magnetic resonance imaging revealed bone destruction and an adjacent soft tissue mass at the right scapula. The findings on computed tomography imaging were compatible with cholangiocarcinoma. Bone biopsy was performed and the diagnosis of cholangiocarcinoma with bone metastasis was confirmed. The survival time was 10 months, despite administration of palliative radiotherapy and chemotherapy. Therefore, bone metastasis from cholangiocarcinoma should be considered as a differential diagnosis in patients who present with an osteolytic bone lesion and a liver mass.
胆管癌是肝胆道系统的一种侵袭性肿瘤，通常会扩散至区域淋巴结、肝脏和肺部。然而，与其他肿瘤相比，胆管癌的骨转移较为罕见。我们在此报告一例61岁的亚洲女性病例，该患者以右肩胛区疼痛就诊。磁共振成像显示右肩胛骨骨质破坏及相邻软组织肿块。计算机断层扫描成像结果与胆管癌相符。进行了骨活检，确诊为胆管癌伴骨转移。尽管给予了姑息性放疗和化疗，患者的生存时间仍为10个月。因此，对于出现溶骨性骨病变和肝脏肿块的患者，应考虑胆管癌骨转移作为鉴别诊断。
