Cordeiro de Souza Leonardo, de Souza Amarildo Abreu, de Almeida Eric Eduardo Pinto, Honse Ribeiro Leo, Parada Godoy Marcos David, Augusto Junior Wanderlei, Ronaldo Lugon Jocemir
Medical Science Post-Graduation Program, Universidade Federal Fluminense, Niterói, RJ, Brazil.
Intensive Care Division, Hospital e Clínica São Gonçalo, São Gonçalo, RJ, Brazil.
Case Rep Crit Care. 2018 Oct 4;2018:9708451. doi: 10.1155/2018/9708451. eCollection 2018.
Zika is an arbovirus infection mainly transmitted by the mosquito . In 2016, the burden of Zika epidemic in Brazil was significant. Patients affected by Zika virus can develop Guillain-Barré syndrome, evolving to muscle respiratory failure requiring mechanical ventilation. In this setting, delayed recovery of the muscle weakness can result in prolonged weaning, a condition that by itself is related to a high mortality rate. The study is reporting a case of a patient with Zika and Guillain-Barré syndrome who underwent an inspiratory muscle training program starting after twenty-five days of mechanical ventilation and guided by serial measurements of the timed inspiratory effort (TIE) index. The patient was successfully weaned in two weeks and discharged from the hospital 30 days after extubation.
寨卡病毒是一种主要由蚊子传播的虫媒病毒感染。2016年,巴西寨卡疫情的负担十分严重。感染寨卡病毒的患者可能会发展为格林-巴利综合征,进而演变为需要机械通气的肌肉呼吸衰竭。在这种情况下,肌肉无力恢复延迟会导致撤机时间延长,而这一情况本身就与高死亡率相关。该研究报告了一例寨卡病毒感染合并格林-巴利综合征的患者,该患者在机械通气25天后开始接受吸气肌训练计划,并以定时吸气努力(TIE)指数的系列测量结果为指导。患者在两周内成功撤机,并在拔管后30天出院。