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韩国近 10 年尿石症患病率和发病率的研究:国家健康保险数据分析。

Study on the prevalence and incidence of urolithiasis in Korea over the last 10 years: An analysis of National Health Insurance Data.

机构信息

Department of Urology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Uijeongbu, Korea.

出版信息

Investig Clin Urol. 2018 Nov;59(6):383-391. doi: 10.4111/icu.2018.59.6.383. Epub 2018 Oct 23.

Abstract

PURPOSE

We aimed to analyze the incidence and prevalence of urolithiasis in Korea over the last decade using the National Health Insurance (NHI) sample cohort data.

MATERIALS AND METHODS

From January 2002 to December 2013, we enrolled sample cohort data from the NHI. Patients diagnosed with international classification of diseases code N20 or N13.2 were included. The incidence and prevalence rate was counted from the same period and patients previously diagnosed with urolithiasis were excluded. We compared the incidence and prevalence of urolithiasis by region, age, and sex, and identified the changes.

RESULTS

Total 1,111,828 subjects were included. Of these subjects, 36,857 had urolithiasis. The male-to-female ratio was 1.57:1, and total incidence rate was 3.27 per 1,000 person-years (1,000p-yrs). The annual incidence was lowest in 2013 (3,138 patients) and highest in 2005 (3,751 patients). Incidence rate by diagnostic code was highest in ureter stone only (2.49 per 1,000p-yrs) and was lowest in kidney and ureter stone both (0.17 per 1,000p-yrs). Prevalence gradually increased from 3,172 in 2002 and 5,758 in 2013. Jeollanam-do had the highest incidence rate of 3.70 persons per 1,000p-yrs, and Jeju had the lowest rate of 2.84 persons per 1,000p-yrs. In gender analysis, Daegu had the highest incidence (4.56) in males, Jeollanam-do had the highest incidence (3.20) in females.

CONCLUSIONS

Annual incidence remained stable, whereas prevalence gradually increased. The incidence in male was 1.57 times higher than female, and the peak incidence age was 45-49 years, with the highest incidence occurring in Jeollanam-do and the lowest in Jeju.

摘要

目的

本研究旨在利用韩国国民健康保险(NHI)抽样队列数据,分析过去十年间韩国尿路结石的发病率和患病率。

材料与方法

本研究纳入了 2002 年 1 月至 2013 年 12 月 NHI 的抽样队列数据。纳入国际疾病分类(ICD)编码为 N20 或 N13.2 的患者。统计同期发病率和患病率,排除既往诊断为尿路结石的患者。我们比较了不同地区、年龄和性别的尿路结石发病率和患病率,并分析了其变化情况。

结果

共纳入 1111828 例患者,其中 36857 例患者患有尿路结石。男女性别比为 1.57:1,总发病率为 3.27/1000 人年(1000p-yrs)。2013 年的年发病率最低(3138 例),2005 年的年发病率最高(3751 例)。按诊断代码计算,输尿管结石的发病率最高(2.49/1000p-yrs),肾结石和输尿管结石同时存在的发病率最低(0.17/1000p-yrs)。患病率从 2002 年的 3172 例逐渐增加至 2013 年的 5758 例。全罗南道的发病率最高,为 3.70/1000p-yrs,济州道的发病率最低,为 2.84/1000p-yrs。在性别分析中,大邱的男性发病率最高(4.56),全罗南道的女性发病率最高(3.20)。

结论

尿路结石的年发病率保持稳定,而患病率逐渐增加。男性的发病率是女性的 1.57 倍,发病高峰年龄为 45-49 岁,发病率最高的地区是全罗南道,最低的地区是济州道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89ab/6215783/151f0ca5c83c/icu-59-383-g001.jpg

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