Department of Urology, Seoul National University Hospital, Seoul, Korea.
Department of Urology, SMG-SNU Boramae Medical Center, Seoul, Korea.
Investig Clin Urol. 2018 Mar;59(2):106-111. doi: 10.4111/icu.2018.59.2.106. Epub 2018 Feb 5.
Dietary factors are one of the main causes of urolithiasis. However, little research has evaluated dietary factors related to urolithiasis in Korea. We investigated the various dietary risk factors for urinary stone formation in Korean people.
We conducted a prospective case-control pilot study. A total of 27 patients newly diagnosed with urolithiasis and 20 applicants without urolithiasis were designated as the patients and the control group, respectively. A face-to-face survey was carried out using a food-frequency questionnaire. After adjustment for physical activity level and total energy intake, multivariate logistic regression models were applied to search for risk factors for urolithiasis.
There were no significant differences between the two groups in gender, age, body mass index, family history, or total energy intake. The physical activity level of the control group was significantly higher than that of the patients (p=0.012). The results of the multivariate logistic regression model demonstrated that intake of carbohydrate (odds ratio [OR], 1.055; 95% confidence interval [CI], 1.012-1.099), protein (OR, 1.101; 95% CI, 1.001-1.211), and cereals (OR, 1.012; 95% CI, 1.002-1.023) could increase the risk for urolithiasis.
A higher intake of carbohydrate, protein, and cereal may increase the risk of urinary stone formation among Korean people.
饮食因素是尿路结石的主要病因之一。然而，针对韩国与尿路结石相关的饮食因素，相关研究甚少。本研究旨在调查韩国人群尿路结石形成的各种饮食风险因素。
我们开展了一项前瞻性病例对照初步研究。共纳入 27 例新诊断为尿路结石的患者和 20 例无尿路结石的申请人员，分别作为患者组和对照组。采用食物频率问卷进行面对面调查。在调整体力活动水平和总能量摄入后，应用多变量逻辑回归模型来寻找尿路结石的危险因素。
两组在性别、年龄、体重指数、家族史或总能量摄入方面无显著差异。对照组的体力活动水平显著高于患者组（p=0.012）。多变量逻辑回归模型的结果表明，碳水化合物（比值比[OR]，1.055；95%置信区间[CI]，1.012-1.099）、蛋白质（OR，1.101；95% CI，1.001-1.211）和谷物（OR，1.012；95% CI，1.002-1.023）的摄入量增加均可增加尿路结石的发病风险。
较高的碳水化合物、蛋白质和谷物摄入可能会增加韩国人群尿路结石形成的风险。
