Lee Seokhan, Kwon Yeongkeun, Lee Nojin, Bae Keun-Joo, Kim Jihyun, Park Seokwon, Kim Yang Hyun, Cho Kyung-Hwan
Department of Family Medicine, Korea University College of Medicine, Seoul, Korea.
Korean J Fam Med. 2019 May;40(3):171-175. doi: 10.4082/kjfm.17.0090. Epub 2018 Nov 8.
Knee osteoarthritis is highly prevalent, especially among the elderly. However, its risk factors have not been well identified, especially in the Korean population. This study aimed to assess the epidemiologic characteristics and risk factors of knee osteoarthritis in the Korean population.
Data of 2,280 (1,295 women) participants of the 2013 Korea National Health and Nutrition Examination Survey aged ≥50 years who underwent knee radiography were analyzed. According to the American College of Rheumatology clinical/radiographic classification criteria, knee osteoarthritis was defined as knee pain and radiographic knee osteoarthritis. The association between risk factors and knee osteoarthritis was analyzed using the chi-square test and binominal logistic regression.
The participants had an average age of 62.6 years; 56.8% of them were women. The average body mass index was 24.2 kg/m2 , and 296 (13%) participants were diagnosed with knee osteoarthritis. After adjustment for multiple risk factors, age of ≥65 years (adjusted odds ratio [OR], 2.552; 95% confidence interval [CI], 1.868-3.486), female sex (OR, 2.050; 95% CI, 1.275-3.295), obesity (body mass index, ≥25.0 kg/m2 ; OR, 1.563; 95% CI, 1.191-2.051), hypertension (OR, 1.394; 95% CI, 1.052-1.846), low educational level (lower than or equal to elementary school: OR, 4.761; 95% CI, 2.131-10.635; middle school: OR, 3.184; 95% CI, 1.375-7.369), and low strength exercise frequency (<2 times/wk; OR, 1.829; 95% CI, 1.202-2.784) increased the risk of knee osteoarthritis.
Old age, sex, obesity, hypertension, low educational level, and low strength exercise frequency were found to be risk factors for knee osteoarthritis.
膝关节骨关节炎非常普遍，尤其是在老年人中。然而，其危险因素尚未得到很好的确定，尤其是在韩国人群中。本研究旨在评估韩国人群中膝关节骨关节炎的流行病学特征和危险因素。
分析了2013年韩国国家健康与营养检查调查中2280名（1295名女性）年龄≥50岁且接受膝关节X线检查的参与者的数据。根据美国风湿病学会临床/影像学分类标准，膝关节骨关节炎定义为膝关节疼痛和影像学膝关节骨关节炎。使用卡方检验和二项逻辑回归分析危险因素与膝关节骨关节炎之间的关联。
参与者的平均年龄为62.6岁；其中56.8%为女性。平均体重指数为24.2kg/m²，296名（13%）参与者被诊断为膝关节骨关节炎。在对多种危险因素进行调整后，年龄≥65岁（调整后的优势比[OR]，2.552；95%置信区间[CI]，1.868 - 3.486）、女性（OR，2.050；95%CI，1.275 - 3.295）、肥胖（体重指数≥25.0kg/m²；OR，1.563；95%CI，1.191 - 2.051）、高血压（OR，1.394；95%CI，1.052 - 1.846）、低教育水平（小学及以下：OR，4.761；95%CI，2.131 - 10.635；初中：OR，3.184；95%CI，1.375 - 7.369）以及低强度运动频率（<2次/周；OR，1.829；95%CI，1.202 - 2.784）会增加膝关节骨关节炎的风险。
年龄、性别、肥胖、高血压、低教育水平和低强度运动频率被发现是膝关节骨关节炎的危险因素。
