山茱萸果实中的环烯醚萜苷
Iridoid glycosides from the fruits of Cornus officinalis.
作者信息
Wang Xin, Liu Chong-Hui, Li Jin-Jie, Zhang Bo, Ji Lin-Lin, Shang Xiao-Ya
机构信息
a Beijing Key Laboratory of Bioactive Substances and Functional Foods , Beijing Union University , Beijing 100191 , China.
出版信息
J Asian Nat Prod Res. 2018 Oct;20(10):934-942. doi: 10.1080/10286020.2018.1497609. Epub 2018 Nov 8.
Four new iridoid glycosides named cornusphenosides A-D (1-4) were isolated from an ethanol extract of the fruits of Cornus officinalis (shan zhu yu). The structures of these compounds were elucidated on the basis of spectroscopic data (UV, IR, HRESIMS, and 1D and 2D NMR) and chemical evidence. The neuroprotective effects of compounds 1-4 were also assessed in vitro.
从山茱萸果实的乙醇提取物中分离出四种新的环烯醚萜苷，命名为山茱萸酚苷A-D（1-4）。根据光谱数据（紫外、红外、高分辨电喷雾电离质谱以及一维和二维核磁共振）和化学证据确定了这些化合物的结构。还在体外评估了化合物1-4的神经保护作用。
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