a Department of Psychology , Stony Brook University , Stony Brook, NY , United States.
b Department of Psychology , University of California , Davis, CA , United States.
Attach Hum Dev. 2019 Feb;21(1):5-22. doi: 10.1080/14616734.2018.1541513. Epub 2018 Nov 8.
In the current pilot study, we examined whether insecure or disorganized attachment was associated with elevated inflammation (i.e. C-reactive protein [CRP]) in children with histories of child protective services (CPS) involvement, and whether early childhood CRP predicted body mass index (BMI) in middle childhood. Participants included 45 CPS-referred children and 39 low-risk comparison children, for whom we assessed levels of CRP in early childhood (Mean age = 4.9 years). For the CPS-referred children, who were drawn from an ongoing longitudinal study, we had attachment classifications (assessed during infancy with the Strange Situation) and BMI data (assessed during early and middle childhood); these data were not available for the low-risk comparison group. CPS-referred children who had insecure or disorganized attachments during infancy had higher levels of CRP in early childhood than CPS-referred children who had secure attachments, who had similar levels of CRP to low-risk comparison children. Among CPS-referred children, early childhood CRP predicted age 8 BMI, controlling for BMI at age 4. Findings offer preliminary support for the association between attachment quality and inflammation in early childhood, which may have implications for later physical health.
在当前的初步研究中，我们研究了儿童保护服务（CPS）介入史的儿童中不安全或失调的依恋是否与炎症升高（即 C 反应蛋白（CRP））有关，以及早期儿童 CRP 是否预测儿童中期的体重指数（BMI）。参与者包括 45 名 CPS 转介儿童和 39 名低风险对照组儿童，我们评估了他们在幼儿期（平均年龄为 4.9 岁）的 CRP 水平。对于来自正在进行的纵向研究的 CPS 转介儿童，我们有依恋分类（在婴儿期用陌生情境评估）和 BMI 数据（在幼儿期和儿童中期评估）；这些数据不适用于低风险对照组。在婴儿期具有不安全或失调依恋的 CPS 转介儿童的 CRP 水平在幼儿期比具有安全依恋的 CPS 转介儿童高，而具有安全依恋的 CPS 转介儿童与低风险对照组儿童的 CRP 水平相似。在 CPS 转介儿童中，早期 CRP 预测 8 岁时的 BMI，控制了 4 岁时的 BMI。这些发现初步支持了幼儿期依恋质量与炎症之间的关联，这可能对以后的身体健康有影响。
