Gilmore Jordon, Islam Monsur, Martinez-Duarte Rodrigo
Mechanical Engineering Department, Clemson University, Clemson, SC 29634, USA.
Micromachines (Basel). 2016 Mar 24;7(4):52. doi: 10.3390/mi7040052.
Since its inception, Compact Disc (CD)-based centrifugal microfluidic technology has drawn a great deal of interest within research communities due to its potential use in biomedical applications. The technology has been referred to by different names, including compact-disc microfluidics, lab-on-a-disk, lab-on-a-CD and bio-disk. This paper critically reviews the state-of-the-art in CD-based centrifugal microfluidics devices and attempts to identify the challenges that, if solved, would enable their use in the extreme point of care. Sample actuation, manufacturing, reagent storage and implementation, target multiplexing, bio-particle detection, required hardware and system disposal, and sustainability are the topics of focus.
自问世以来，基于光盘（CD）的离心微流控技术因其在生物医学应用中的潜在用途而在研究界引起了广泛关注。该技术有不同的名称，包括光盘微流控、芯片实验室、光盘上的实验室和生物光盘。本文对基于CD的离心微流控设备的最新技术进行了批判性综述，并试图找出那些若能解决就能使其在极端即时护理中得以应用的挑战。样品驱动、制造、试剂储存与应用、目标多重分析、生物颗粒检测、所需硬件及系统处置以及可持续性是重点关注的主题。
