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眼球摘除术后用脐带羊膜重建:病例报告

Reconstruction with umbilical amnion following ocular evisceration: A case study.

作者信息

Bunin Lisa S

机构信息

Private Practice, 1611 Pond Rd #403, Allentown, PA, 18104, USA.

出版信息

Am J Ophthalmol Case Rep. 2022 Mar 1;26:101462. doi: 10.1016/j.ajoc.2022.101462. eCollection 2022 Jun.

DOI:10.1016/j.ajoc.2022.101462
PMID:35265778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8899220/
Abstract

PURPOSE

To report the use of cryopreserved amniotic membrane from the umbilical cord (UC) in the reconstruction of a dehisced wound with the additional ability to increase orbital volume, expand superior and inferior fornices, and improve cosmesis following evisceration of a blind, painful, atrophic, sunken eye with ptosis.

OBSERVATIONS

Patient developed conjunctival wound dehiscence without implant exposure following evisceration. One month later, reconstruction was performed with UC to cover the defect, increase the orbital volume, and expand orbital fornices to allow placement of a large ocular prosthesis with superior lip for ptosis elevation. Post-operatively, at the 6th week, the socket was healthy and the globe had good movement. At the 7th week, the ocular prosthesis was sized and fitted. At the 8th month, the structural integrity of the socket was maintained with deep fornices, and the patient had excellent cosmetic result with natural appearance and movement of the prosthetic eye.

CONCLUSIONS AND IMPORTANCE

This case highlights the successful utilization of UC graft to augment soft tissue volume, restore socket structural integrity and increase socket volume, and achieve good cosmesis and ocular motility following evisceration.

摘要

目的

报告使用来自脐带的冷冻保存羊膜在裂开伤口重建中的应用,其具有增加眼眶容积、扩大上下穹窿以及改善因失明、疼痛、萎缩、凹陷且伴有上睑下垂的眼球摘除术后美观效果的额外能力。

观察结果

患者在眼球摘除术后出现结膜伤口裂开但植入物未外露。1个月后,使用脐带进行重建以覆盖缺损、增加眼眶容积并扩大眼眶穹窿,从而能够放置大型眼假体以抬高上睑。术后第6周,眼窝健康,眼球活动良好。第7周,确定眼假体尺寸并进行安装。第8个月,眼窝结构完整性得以维持,穹窿较深,患者的义眼外观自然且活动良好,美容效果极佳。

结论与意义

该病例突出了脐带移植物在增加软组织容积、恢复眼窝结构完整性和增大眼窝容积方面的成功应用,并在眼球摘除术后实现了良好的美容效果和眼球活动度。

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引用本文的文献

1
The current alternative for ocular surface and anophthalmic socket reconstruction, cryopreserved umbilical amniotic membrane (cUAM).目前,眼表和眼窝再造的替代方法是冷冻保存的脐带羊膜(cUAM)。
Int Ophthalmol. 2024 Jun 25;44(1):274. doi: 10.1007/s10792-024-03232-4.

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Complications after Modified Evisceration with Closure of the Anterior Scleral Shell by Donor Scleral Graft.采用供体巩膜移植封闭前巩膜壳改良眼内容剜出术后的并发症
Klin Monbl Augenheilkd. 2021 Apr;238(4):358-360. doi: 10.1055/a-1386-5634. Epub 2021 Apr 30.
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Anophthalmic Ptosis and the Effects of Enucleation on Upper Eyelid Function.先天性上睑下垂和眼球摘除对上睑功能的影响。
Ophthalmic Plast Reconstr Surg. 2021;37(3S):S80-S84. doi: 10.1097/IOP.0000000000001823.
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Outcomes of the Shunt Tube Exposure Prevention Study: A Randomized Clinical Trial.
分流管暴露预防研究的结果:一项随机临床试验。
Ophthalmol Glaucoma. 2019 Nov-Dec;2(6):392-401. doi: 10.1016/j.ogla.2019.08.003. Epub 2019 Aug 16.
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Basic science review of birth tissue uses in ophthalmology.眼科中出生组织应用的基础科学综述
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The Use of Umbilical Amnion for Conjunctival Socket, Fornix, and Eyelid Margin Reconstruction.脐带羊膜在结膜囊、穹窿和眼睑缘重建中的应用。
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Novel Use of Cryopreserved Ultra-thick Human Amniotic Membrane for Management of Anophthalmic Socket Contracture.冷冻保存的超厚人羊膜在无眼窝畸形中的应用
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