Balaji S M, Balaji Preetha
Director and Consultant, Department of Oral and Maxillofacial Surgery, Balaji Dental and Craniofacial Hospital, Chennai, Tamil Nadu, India.
Consultant, Department of Oral and Maxillofacial Surgery, Balaji Dental and Craniofacial Hospital, Chennai, Tamil Nadu, India.
Indian J Dent Res. 2018 Sep-Oct;29(5):687-689. doi: 10.4103/ijdr.IJDR_651_18.
Granular cell tumor (GCT) is a rare soft-tissue neoplasm, first described in 1926. GCT often manifests as a single, painless nodule that shows a slow enlargement in the cutaneous, subcutaneous, or submucosal tissues. It is commonly reported in adults in the third to sixth decade of life. This case report is of an incidental finding in a young boy, who was radiologically examined for orthodontic treatment purpose and found to have a radiolucent lesion in the mandible. The lesion was later diagnosed as GCT. Central GCT is rare, and the presentation in a child is even rare. Although GCT is reported to be benign, it can turn malignant in 2% of the cases and possibly metastasize too. The local recurrence within a year is characteristic for malignant GCT. The 1-year follow-up of the present case indicated no local recurrence. The case stresses the need for the frequent dental examination, specialist reference. GCT should be included in the differential diagnosis of head and neck masses, even when inside jaws. It shall be remembered that such tumors may arise in any atypical locations and there is a possibility of malignancy.
颗粒细胞瘤（GCT）是一种罕见的软组织肿瘤，于1926年首次被描述。GCT常表现为单个无痛性结节，在皮肤、皮下或粘膜下组织中缓慢增大。常见于30至60岁的成年人。本病例报告是关于一名小男孩的偶然发现，他因正畸治疗目的接受放射检查时，发现下颌骨有一个透光性病变。该病变后来被诊断为GCT。中枢性GCT罕见，在儿童中出现更为罕见。尽管GCT据报道为良性，但在2%的病例中可能会恶变并可能发生转移。恶性GCT的特征是在一年内局部复发。本病例的1年随访表明无局部复发。该病例强调了频繁进行牙科检查、转诊至专科医生的必要性。即使GCT位于颌骨内，也应将其纳入头颈部肿块的鉴别诊断中。应记住，此类肿瘤可能出现在任何非典型部位，并且有恶变的可能性。
