Ma Jianhua, Cheng Yicheng, Li Xue, Liu Wei, Liu Renghai, Liu Chuanbo
Department of Anorectal Surgery, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Department of Anorectal Surgery, China-Japan Friendship Hospital, Beijing, China.
J Int Med Res. 2021 Jan;49(1):300060520982689. doi: 10.1177/0300060520982689.
Granular cell tumors (GCTs) are rare submucosal neoplasms, with tumors in the oral mucosa accounting for about a third of all cases. In contrast, GCT is a rare anal neoplasm, with fewer than 30 cases of perianal GCT reported in the literature. We report the case of a 36-year-old woman with a perianal lump with no obvious local lesion as the main clinical complaint. The tumor was completely resected and histologically confirmed as a GCT. The patient remained under continuous follow-up. GCT is difficult for surgeons and pathologists to diagnose, and biopsy and immunohistochemical analysis are prerequisites for an accurate diagnosis. An integrated understanding of GCT in terms of its differential diagnosis will contribute to better identification and more appropriate treatment of this disease.
颗粒细胞瘤(GCTs)是罕见的黏膜下肿瘤,口腔黏膜肿瘤约占所有病例的三分之一。相比之下,GCT是一种罕见的肛门肿瘤,文献报道的肛周GCT病例少于30例。我们报告了一例36岁女性,以肛周肿块为主诉,无明显局部病变。肿瘤被完整切除,组织学确诊为GCT。患者持续接受随访。GCT对外科医生和病理学家来说诊断困难,活检和免疫组化分析是准确诊断的前提条件。从鉴别诊断的角度综合了解GCT将有助于更好地识别和更恰当地治疗这种疾病。