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辐射诱发的冠状动脉疾病及其治疗:当前证据的快速回顾

Radiation-Induced Coronary Artery Disease and Its Treatment: A Quick Review of Current Evidence.

作者信息

DeZorzi Christopher

机构信息

University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.

出版信息

Cardiol Res Pract. 2018 Oct 16;2018:8367268. doi: 10.1155/2018/8367268. eCollection 2018.

DOI:10.1155/2018/8367268
PMID:30410795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6206518/
Abstract

As advances in medical technology arise and the availability of cancer treatment increases, an increased number of patients are receiving cancer treatment. Radiation therapy has evolved to become one of the cornerstones of treatment for various types of cancers. One of the long-term consequences of radiation therapy is radiation-induced coronary artery disease (RICAD). Although the pathophysiology of RICAD may be slightly different and more acute onset than the commonly seen "generic" coronary artery disease, it is common practice to treat RICAD in the same method as nonradiation-induced CAD. This paper summarizes the current research available on the topic and shows there is not enough research to obtain significant data about outcomes and restenosis rates of PCI or outcomes of CABG in RICAD. The aim of this review is to create a concise and easy-to-follow review of the relevant data regarding RICAD and hopefully spark further interest in future studies in this field.

摘要

随着医学技术的进步以及癌症治疗可及性的提高,接受癌症治疗的患者数量不断增加。放射治疗已发展成为各类癌症治疗的基石之一。放射治疗的长期后果之一是放射性冠状动脉疾病(RICAD)。尽管RICAD的病理生理学可能与常见的“普通”冠状动脉疾病略有不同且发病更急,但通常采用与非放射诱导的冠心病相同的方法来治疗RICAD。本文总结了该主题的现有研究,结果表明,目前尚无足够的研究来获取关于RICAD患者经皮冠状动脉介入治疗(PCI)的结局和再狭窄率或冠状动脉旁路移植术(CABG)结局的重要数据。本综述的目的是对有关RICAD的相关数据进行简明且易于理解的综述,并有望激发该领域未来研究的更多兴趣。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e80/6206518/815c30374fd2/CRP2018-8367268.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e80/6206518/b50086bbe08e/CRP2018-8367268.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e80/6206518/815c30374fd2/CRP2018-8367268.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e80/6206518/b50086bbe08e/CRP2018-8367268.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e80/6206518/815c30374fd2/CRP2018-8367268.002.jpg

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Long-Term Cardiovascular Risk After Radiotherapy in Women With Breast Cancer.乳腺癌女性放疗后的长期心血管风险
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Long-Term Mortality in Patients With Radiation-Associated Coronary Artery Disease Treated With Percutaneous Coronary Intervention.接受经皮冠状动脉介入治疗的放射性相关冠状动脉疾病患者的长期死亡率
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Radiation-induced coronary artery disease: Useful insights from OCT.
放射性冠状动脉疾病:一个棘手的临床难题。
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