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A、B、C和G组β溶血性链球菌败血症:一项临床研究。

Beta-haemolytic group A, B, C and G streptococcal septicaemia: a clinical study.

作者信息

Skogberg K, Simonen H, Renkonen O V, Valtonen V V

机构信息

Department of Bacteriology and Immunology, University of Helsinki, Finland.

出版信息

Scand J Infect Dis. 1988;20(2):119-25. doi: 10.3109/00365548809032427.

Abstract

87 beta-haemolytic streptococcal septicaemias in adult patients during 1979-86 in a university hospital were reviewed. 25% were caused by group A streptococcus, 17% by group B, 14% by group C and 44% by group G streptococcus. 67% of the septicaemias due to group B streptococcus were nosocomial, whereas the group A, C or G septicaemias were in most cases community-acquired. Alcoholism was the most common underlying disease in group A (32%) and malignancy in group G streptococcal septicaemias (45%). The most common origin and focus of infection in group A, C and G streptococcal septicaemias was the skin. The total mortality in beta-haemolytic streptococcal septicaemias was 20%, higher in septicaemias caused by group A (32%) and group B (33%) than by group C (17%) and group G (8%) streptococci. Nevertheless, there were more patients in group G streptococcal septicaemias with severe underlying diseases than in other groups of beta-haemolytic streptococci. The present data seem to indicate that a septicaemia due to group G is a more benign disease than a septicaemia due to group A streptococcus.

摘要

回顾了1979年至1986年期间一所大学医院成年患者中87例β溶血性链球菌败血症病例。其中25%由A组链球菌引起,17%由B组引起,14%由C组引起,44%由G组链球菌引起。B组链球菌所致败血症中67%为医院内感染,而A组、C组或G组败血症大多数为社区获得性感染。酗酒是A组链球菌败血症(32%)最常见的基础疾病,恶性肿瘤是G组链球菌败血症(45%)最常见的基础疾病。A组、C组和G组链球菌败血症最常见的感染源和病灶是皮肤。β溶血性链球菌败血症的总死亡率为20%,A组(32%)和B组(33%)引起的败血症死亡率高于C组(17%)和G组(8%)链球菌引起的败血症。然而,G组链球菌败血症患者中患有严重基础疾病的人数比其他β溶血性链球菌组更多。目前的数据似乎表明,G组链球菌引起的败血症比A组链球菌引起的败血症病情更轻。

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