Sex Transm Dis. 2018 Dec;45(12):798-802. doi: 10.1097/OLQ.0000000000000880.
Preexposure prophylaxis (PrEP) reduces risk of human immunodeficiency virus infection for many gay and bisexual men (GBM); however, bacterial sexually transmitted infections associated with decreasing condom use among users is of concern. Center for Disease Control and Prevention's guidelines for PrEP use recommend bacterial sexually transmitted infection screening every 6 months. We sought to investigate comprehensive PrEP care, defined as: (1) discussion of sexual behavior, (2) blood sample, (3) urine sample, (4) rectal sample (rectal swab), and (5) throat sample (throat swab), provided at the user's last PrEP appointment.
The PrEP-using GBM in New York City (n = 104) were asked about their last PrEP care visit. We examined associations of demographics (age, race/ethnicity, and education), recent number of condomless anal sex events, time on PrEP, and health care provider type on receiving comprehensive care at last visit using fully adjusted binary logistic regression.
At their last visit, nearly all men (94%) gave blood for testing, 88% provided a urine sample, and 77% discussed sexual behavior with their provider. However, only 51% reported having a rectal swab, and 48% an oral swab. Only 32% of men received comprehensive PrEP care at their last PrEP visit. Odds of receiving comprehensive care were significantly higher among younger men, men with a bachelor's degree or more education, and those who reported more condomless anal sex.
Less than one third of GBM received comprehensive human immunodeficiency virus/sexually transmitted infection counseling and testing at their last visit. These findings indicate further efforts are needed to prepare health care providers for prescribing and managing patients on PrEP.
暴露前预防(PrEP)可降低许多男同性恋和双性恋者(GBM)感染人类免疫缺陷病毒的风险;然而,使用者减少使用避孕套与相关的细菌性性传播感染令人担忧。美国疾病控制与预防中心(CDC)的 PrEP 使用指南建议每 6 个月进行细菌性性传播感染筛查。我们旨在调查综合 PrEP 护理情况,定义为:(1)讨论性行为,(2)采集血样,(3)采集尿样,(4)直肠样本(直肠拭子),和(5)咽喉样本(咽喉拭子),在使用者的最后一次 PrEP 预约时提供。
我们询问了纽约市使用 PrEP 的 GBM(n = 104)关于他们最近一次 PrEP 护理就诊的情况。我们使用完全调整后的二项逻辑回归,检查了人口统计学特征(年龄、种族/族裔和教育程度)、最近无保护肛交事件的数量、使用 PrEP 的时间和医疗保健提供者类型与最后一次就诊时接受全面护理之间的关联。
在最后一次就诊时,几乎所有男性(94%)都提供了血液样本进行检测,88%提供了尿液样本,77%与提供者讨论了性行为。然而,只有 51%的人报告进行了直肠拭子检查,48%的人进行了口腔拭子检查。只有 32%的男性在最后一次 PrEP 就诊时接受了综合 PrEP 护理。在最后一次就诊时接受综合护理的可能性,在较年轻的男性、具有学士或更高学位的男性以及报告更多无保护肛交的男性中显著更高。
不到三分之一的 GBM 在最后一次就诊时接受了全面的人类免疫缺陷病毒/性传播感染咨询和检测。这些发现表明,需要进一步努力使医疗保健提供者为开处方和管理 PrEP 患者做好准备。