Department of Electrical and Electronic Engineering, Yonsei University, Seoul 03722, Korea.
Department of Physics Education, College of Education, Daegu University, Gyeongsan 38453, Korea.
Sensors (Basel). 2018 Nov 9;18(11):3850. doi: 10.3390/s18113850.
In this paper, a fluidic glucose sensor that is based on a complementary split-ring resonator (CSRR) is proposed for the microwave frequency region. The detection of glucose with different concentrations from 0 mg/dL to 400 mg/dL in a non-invasive manner is possible by introducing a fluidic system. The glucose concentration can be continuously monitored by tracking the transmission coefficient S 21 as a sensing parameter. The variation tendency in S 21 by the glucose concentration is analyzed with equivalent circuit model. In addition, to eradicate the systematic error due to temperature variation, the sensor is tested in two temperature conditions: the constant temperature condition and the time-dependent varying temperature condition. For the varying temperature condition, the temperature correction function was derived between the temperature and the variation in S 21 for DI water. By applying the fitting function to glucose solution, the subsidiary results due to temperature can be completely eliminated. As a result, the S 21 varies by 0.03 dB as the glucose concentration increases from 0 mg/dL to 400 mg/dL.
本文提出了一种基于互补分裂环谐振器(CSRR)的流体葡萄糖传感器,用于微波频率区域。通过引入流体系统,可以非侵入式地检测 0 mg/dL 至 400 mg/dL 之间不同浓度的葡萄糖。通过跟踪传输系数 S 21 作为传感参数,可以连续监测葡萄糖浓度。通过等效电路模型分析 S 21 随葡萄糖浓度的变化趋势。此外,为了消除因温度变化引起的系统误差,传感器在两种温度条件下进行测试:恒温条件和时变温度条件。对于时变温度条件,推导了 DI 水的温度和 S 21 变化之间的温度校正函数。通过将拟合函数应用于葡萄糖溶液,可以完全消除因温度引起的副效应。结果,当葡萄糖浓度从 0 mg/dL 增加到 400 mg/dL 时,S 21 变化了 0.03 dB。