Perttilä J, Salo M, Peltola O, Irjala K
Department of Anaesthesiology, University of Turku, Finland.
Eur Surg Res. 1988;20(3):211-9. doi: 10.1159/000128763.
Chemiluminescence activity of granulocytes in phagocytosis of zymosan and Escherichia coli and their responses to chemoattractant N-formylmethionyl-leucyl-phenylalanine (FMLP) were evaluated in 13 major blunt trauma patients (Injury Severity Score 31 +/- 6) and their plasma fibronectin concentrations were measured. Chemiluminescence responses to zymosan and E. coli were at control levels immediately after injury and a week thereafter, but responses to FMLP were increased compared to the controls (p less than 0.05). Plasma fibronectin concentrations were depressed on the day after trauma (p less than 0.001) but increased to control values over 1 week. The changes had no correlation with the patients' recovery.
对13例主要钝性创伤患者（损伤严重度评分31±6），评估了其粒细胞在吞噬酵母聚糖和大肠杆菌时的化学发光活性以及它们对趋化因子N-甲酰甲硫氨酰-亮氨酰-苯丙氨酸（FMLP）的反应，并测定了其血浆纤维连接蛋白浓度。创伤后即刻及1周后，对酵母聚糖和大肠杆菌的化学发光反应处于对照水平，但对FMLP的反应较对照组增强（p<0.05）。创伤后第1天血浆纤维连接蛋白浓度降低（p<0.001），但1周后升至对照值。这些变化与患者的恢复情况无关。
