脑膜炎奈瑟菌携带情况：在一个军事机构中的调查
Carriage of Neisseria meningitidis: investigations in a military establishment.
作者信息
Pether J V, Lightfoot N F, Scott R J, Morgan J, Steele-Perkins A P, Sheard S C
机构信息
Public Health Laboratory Service, Taunton Hospital, Musgrove Park Branch.
出版信息
Epidemiol Infect. 1988 Aug;101(1):21-42. doi: 10.1017/s0950268800029198.
Abstract
A prevalence study of personnel on a Royal Naval Air Station revealed that 23.0% of 2479 personnel were carrying a meningococcus. Selected groups of personnel were subsequently swabbed monthly for a year. We have shown that it is only by repeated swabbing and the use of optimal methods including enrichment media that one can have a hope of identifying the 'true' carriage rate. A presumed virulent strain of Neisseria meningitidis B15 P1.16 was repeatedly isolated from three personnel who remained well, as did their colleagues both at their work place and socially. The study served to emphasize our lack of knowledge of the virulence factors associated with N. meningitidis.
摘要
一项对皇家海军航空站人员的患病率研究表明，2479名人员中有23.0%携带脑膜炎球菌。随后，选定的人员组每月进行拭子采样，持续一年。我们已经表明，只有通过反复拭子采样并使用包括增菌培养基在内的最佳方法，才有望确定“真正”的携带率。从三名一直健康的人员以及他们在工作场所和社交场合的同事身上反复分离出一种推测为有毒力的B15 P1.16型脑膜炎奈瑟菌菌株。该研究强调了我们对与脑膜炎奈瑟菌相关的毒力因子缺乏了解。
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