Blackwell C C, Tzanakaki G, Kremastinou J, Weir D M, Vakalis N, Elton R A, Mentis A, Fatouros N
Department of Medical Microbiology, Medical School, University of Edinburgh.
Epidemiol Infect. 1992 Jun;108(3):441-8. doi: 10.1017/s0950268800049943.
Greek military recruits (993) were examined for carriage of meningococci during July 1990. Blood, saliva and throat swab specimens were obtained and each recruit answered a questionnaire providing information on age, education (a measure of socioeconomic level), place of residence, smoking habits and recent infections. The overall carriage rate was 25% but differed between the two camps: 79/432 (18%) in Camp A and 168/561 (30%) in Camp B (P less than 0.0005). In Camp B, there were significantly higher proportions of recruits who were non-secretors (P less than 0.0005), and/or heavy smokers (P less than 0.0005). They were also younger (less than 19 years old) (P less than 0.001), and on the whole had fewer years of education (P less than 0.0005). By univariate analysis, carriage was significantly associated with smoking. By multiple logistic regression analysis, carriage was associated with smoking (P less than 0.001), age (P less than 0.01) and the camp in which the recruits were based (P less than 0.01). Among recruits in Camp B, 15/38 (40%) of those with recent viral infections were carriers compared with 30% for the camp in general.
1990年7月，对993名希腊新兵进行了脑膜炎球菌携带情况检查。采集了血液、唾液和咽喉拭子样本，每名新兵都回答了一份问卷，提供了有关年龄、教育程度（社会经济水平的一个衡量指标）、居住地点、吸烟习惯和近期感染情况的信息。总体携带率为25%，但两个营地之间存在差异：A营地为79/432（18%），B营地为168/561（30%）（P<0.0005）。在B营地，非分泌型新兵（P<0.0005）和/或重度吸烟者（P<0.0005）的比例显著更高。他们也更年轻（不到19岁）（P<0.001），总体受教育年限更少（P<0.0005）。通过单因素分析，携带情况与吸烟显著相关。通过多因素逻辑回归分析，携带情况与吸烟（P<0.001）、年龄（P<0.01）以及新兵所在的营地（P<0.01）有关。在B营地的新兵中，近期有病毒感染的新兵中有15/38（40%）是携带者，而该营地总体携带者比例为30%。
