Barberis Claudia M, Montalvo Eduardo, Imas Soledad, Traglia Germán, Almuzara Marisa N, Rodriguez Carlos Hernán, Famiglietti Angela, Mazzocchi Octavio, Vay Carlos
Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, Departamento de Bioquímica Clínica, Cátedra de Microbiología Clínica, Hospital de Clínicas José de San Martín, Ciudad Autónoma de Buenos Aires, Argentina.
Universidad de Buenos Aires. Departamento de Medicina, V Cátedra de Medicina Interna, Hospital de Clínicas José de San Martín, Ciudad Autónoma de Buenos Aires, Argentina.
JMM Case Rep. 2018 Apr 6;5(9):e005149. doi: 10.1099/jmmcr.0.005149. eCollection 2018 Sep.
is a Gram-stain-positive non-lipophilic coryneform rod first described in blood samples and pleural fluid. There is scarce information about the clinical relevance of and none on complicated urinary tract infections has been described so far.
A 36-year-old woman with a history of chronic kidney failure, under thrice-weekly haemodialysis since 2014 due to polycystic kidney disease, presented with hypogastric pain, lower left quadrant pain and nausea. Since 1997, the patient had developed several episodes of urinary tract infection. On admission, the patient presented tenderness in the lower abdomen and fist positive lumbar percussion. Urine culture showed significant bacterial growth (>10 c.f.u. ml). Slightly glistening colonies of 1 mm in diameter were observed after a 24 h incubation. Gram staining showed coryneform Gram-stain-positive rods. The patient was diagnosed as having a complicated urinary tract infection. A bilateral nephrectomy was performed on the fourth day of hospitalization. Two samples of kidney tissue were sent for culture. Direct examination of the material revealed the presence of abundant inflammatory reaction and Gram-positive diphtheroid rods. The organism was identified using MALDI-TOF and conventional biochemical tests; in both isolates further identification was performed by PCR amplification and sequence analysis of the gene as .
is an infrequent species among the genus that should be considered as an emerging pathogen that can be involved in nosocomial infections and complicated urinary tract infections.
[细菌名称]是一种革兰氏染色阳性的非嗜脂性棒状杆菌,最初在血液样本和胸腔积液中被描述。关于[细菌名称]临床相关性的信息很少,迄今为止尚未有关于其导致复杂性尿路感染的报道。
一名36岁女性,有慢性肾衰竭病史,自2014年起因多囊肾病每周进行三次血液透析,出现下腹痛、左下腹疼痛和恶心症状。自1997年以来,该患者曾多次发生尿路感染。入院时,患者下腹部有压痛,左侧腰部叩击痛阳性。尿培养显示有显著细菌生长(>10 c.f.u. / ml)。培养24小时后观察到直径为1毫米的稍带光泽的菌落。革兰氏染色显示为革兰氏阳性棒状杆菌。该患者被诊断为复杂性尿路感染。住院第四天进行了双侧肾切除术。两份肾组织样本送去培养。对样本的直接检查显示存在大量炎症反应和革兰氏阳性类白喉杆菌。使用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF)和传统生化试验鉴定该微生物;对两份分离株均通过PCR扩增和[细菌名称]基因的序列分析进行进一步鉴定。
[细菌名称]是[细菌属名]属中一种罕见的菌种,应被视为一种新兴病原体,可导致医院感染和复杂性尿路感染。