Manschot W A, van Strik R
Institut für Pathologie, Erasmus-Universität, Rotterdam.
Klin Monbl Augenheilkd. 1988 May;192(5):582-5. doi: 10.1055/s-2008-1050183.
An analysis of published results of irradiation of choroidal melanomas shows that only two reports contain justified statistics. All other statistics are based on insufficiently long follow-up periods, and do not cover all patients irradiated so that artifacts of selection occur which cannot be checked. Arguments are adduced which show that the authors of the two relevant reports mentioned rightly changed their previously positive attitude towards irradiation of these tumors. With the exception of three circumscribed categories of patients, irradiation of choroidal melanomas is still an unjustifiable medical experiment.
对已发表的脉络膜黑色素瘤照射结果的分析表明,只有两份报告包含合理的统计数据。所有其他统计数据所依据的随访期不够长,且未涵盖所有接受照射的患者,因此出现了无法核查的选择偏倚。有人提出论据表明,上述两份相关报告的作者正确地改变了他们先前对这些肿瘤照射的积极态度。除了三类特定的患者外,脉络膜黑色素瘤的照射仍然是一项不合理的医学试验。