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脉络膜黑色素瘤的放射治疗:合理的治疗方法还是医学实验

[Irradiation of choroid melanoma: justifiable therapy or medical experiment].

作者信息

Manschot W A, van Strik R

机构信息

Institut für Pathologie, Erasmus-Universität, Rotterdam.

出版信息

Klin Monbl Augenheilkd. 1988 May;192(5):582-5. doi: 10.1055/s-2008-1050183.

DOI:10.1055/s-2008-1050183
PMID:3043103
Abstract

An analysis of published results of irradiation of choroidal melanomas shows that only two reports contain justified statistics. All other statistics are based on insufficiently long follow-up periods, and do not cover all patients irradiated so that artifacts of selection occur which cannot be checked. Arguments are adduced which show that the authors of the two relevant reports mentioned rightly changed their previously positive attitude towards irradiation of these tumors. With the exception of three circumscribed categories of patients, irradiation of choroidal melanomas is still an unjustifiable medical experiment.

摘要

对已发表的脉络膜黑色素瘤照射结果的分析表明,只有两份报告包含合理的统计数据。所有其他统计数据所依据的随访期不够长,且未涵盖所有接受照射的患者,因此出现了无法核查的选择偏倚。有人提出论据表明,上述两份相关报告的作者正确地改变了他们先前对这些肿瘤照射的积极态度。除了三类特定的患者外,脉络膜黑色素瘤的照射仍然是一项不合理的医学试验。

相似文献

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[Irradiation of choroid melanoma: justifiable therapy or medical experiment].脉络膜黑色素瘤的放射治疗:合理的治疗方法还是医学实验
Klin Monbl Augenheilkd. 1988 May;192(5):582-5. doi: 10.1055/s-2008-1050183.
2
[Uveal melanomas and vitreous hemorrhage. Diagnosis and treatment].[葡萄膜黑色素瘤与玻璃体积血。诊断与治疗]
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Planned combined I-125 plaque irradiation and indirect ophthalmoscope laser therapy for choroidal malignant melanoma.计划采用碘-125斑块照射联合间接检眼镜激光疗法治疗脉络膜恶性黑色素瘤。
Ophthalmic Surg. 1993 Feb;24(2):76-81.
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[Treatment of choroid melanoma with contact curietherapy using ruthenium 106].用钌106接触式居里治疗法治疗脉络膜黑色素瘤
J Fr Ophtalmol. 1985;8(10):639-43.
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[The role of beta-ray therapy in the treatment of choroidal and ciliary body melanomas].[β射线疗法在脉络膜和睫状体黑色素瘤治疗中的作用]
Ophtalmologie. 1989 Jun-Aug;3(3):175-9.
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[The regression behavior of choroid melanoma following radiotherapy--a new prognostic parameter?].[放射治疗后脉络膜黑色素瘤的回归行为——一个新的预后参数?]
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Radiotherapy of malignant melanoma of the choroid.脉络膜恶性黑色素瘤的放射治疗
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[Therapy of radiation resistant malignant uveal melanoma with endoresection by pars plana vitrectomy in two patients].[两例采用经扁平部玻璃体切除术进行内切除治疗放射性耐药性恶性葡萄膜黑色素瘤]
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Ten-year follow-up of fellow eyes of patients enrolled in Collaborative Ocular Melanoma Study randomized trials: COMS report no. 22.协作性眼黑色素瘤研究随机试验中入组患者对侧眼的十年随访:COMS报告第22号
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[Initial results in percutaneous radiotherapy of malignant melanomas of the choroid with the linear accelerator].[直线加速器用于脉络膜恶性黑色素瘤经皮放射治疗的初步结果]
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1
Uveal melanoma: therapeutic consequences of doubling times and irradiation results; a review.
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