Lyu G Z
214041 Wuxi, Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City.
Zhonghua Shao Shang Za Zhi. 2018 Nov 9;34(11):E003. doi: 10.3760/cma.j.issn.1009-2587.2018.11.E003.
Collagen, as the main structural protein in human body, plays an important role in the wound healing process. Due to their inherent hemostatic characteristics, good biocompatibility, low immunogenicity, as well as controllable biodegradability, collagen-based materials have attracted much attention. In this article, we mainly introduce the characteristics of collagen-based wound biomaterials and the application mechanism as scaffold and wound dressing. And the standard and unified experts' consensus formed on the clinical indications, recommended applications, contraindications, and matters needing attention. The consensus wound help clinicians and patients to recognize collagen-based wound biomaterials correctly and use them rationally.
胶原蛋白作为人体主要的结构蛋白，在伤口愈合过程中发挥着重要作用。基于胶原蛋白的材料因其固有的止血特性、良好的生物相容性、低免疫原性以及可控的生物降解性而备受关注。在本文中，我们主要介绍了基于胶原蛋白的伤口生物材料的特性以及作为支架和伤口敷料的应用机制。并阐述了在临床适应症、推荐应用、禁忌症及注意事项方面形成的规范统一的专家共识。该共识有助于临床医生和患者正确认识并合理使用基于胶原蛋白的伤口生物材料。
