用于高强度聚焦超声焦点定位的超声声辐射力脉冲成像

Ultrasound Acoustic Radiation Force Impulse imaging for High Intensity Focused Ultrasound focal spot localization.

作者信息

Cafarelli A, Chanel L A, Di Bartolo F, Locteau H, Tognarelli S, Dumont E, Menciassi A

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:5713-5716. doi: 10.1109/EMBC.2018.8513591.

DOI:10.1109/EMBC.2018.8513591

Abstract

Focal spot precise localization highly contributes to the accuracy and safety of High Intensity Focused Ultrasound (HIFU) therapies, and it is usually performed by means of Magnetic Resonance-Acoustic Radiation Force Impulse imaging (MR-ARFI). Acoustic Radiation Force Impulse imaging using ultrasound (US-ARFI) is herein proposed as a valid alternative to MR-ARFI for an accurate and non-destructive detection of the focal spot position during the pre-treatment phase. To this aim, a system composed of a HIFU transducer for generating the acoustic radiation force and a 2D confocal ultrasound probe for measuring the induced micro-displacement have been used. Then, an algorithm based on the Normalized Cross Correlation was implemented for the creation of a displacement map in which the highest displacement area, corresponding to the focal spot region, is unequivocally visualized. The feasibility of the proposed USARFI method for HIFU focal spot localization was successfully demonstrated in a tissue mimicking phantom model.

摘要

焦点精确定位对高强度聚焦超声（HIFU）治疗的准确性和安全性有很大贡献，通常通过磁共振 - 声辐射力脉冲成像（MR - ARFI）来实现。本文提出使用超声的声辐射力脉冲成像（US - ARFI）作为MR - ARFI的有效替代方法，用于在治疗前阶段准确且无损地检测焦点位置。为此，使用了一个由用于产生声辐射力的HIFU换能器和用于测量诱导微位移的二维共聚焦超声探头组成的系统。然后，实施了一种基于归一化互相关的算法来创建位移图，其中对应于焦点区域的最高位移区域被清晰地可视化。所提出的USARFI方法用于HIFU焦点定位的可行性在组织模拟体模模型中得到了成功验证。