• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy.

作者信息

Gubin Matthew M, Esaulova Ekaterina, Ward Jeffrey P, Malkova Olga N, Runci Daniele, Wong Pamela, Noguchi Takuro, Arthur Cora D, Meng Wei, Alspach Elise, Medrano Ruan F V, Fronick Catrina, Fehlings Michael, Newell Evan W, Fulton Robert S, Sheehan Kathleen C F, Oh Stephen T, Schreiber Robert D, Artyomov Maxim N

出版信息

Cell. 2018 Nov 15;175(5):1443. doi: 10.1016/j.cell.2018.11.003.

DOI:10.1016/j.cell.2018.11.003
PMID:30445041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6541402/
Abstract
摘要

相似文献

1
High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy.高维分析描绘了成功的免疫检查点癌症治疗过程中髓系和淋巴系区室的重塑。
Cell. 2018 Nov 15;175(5):1443. doi: 10.1016/j.cell.2018.11.003.
2
Myeloid-Derived Suppressor Cells Hinder the Anti-Cancer Activity of Immune Checkpoint Inhibitors.髓源性抑制细胞阻碍免疫检查点抑制剂的抗癌活性。
Front Immunol. 2018 Jun 11;9:1310. doi: 10.3389/fimmu.2018.01310. eCollection 2018.
3
Propelling Immunotherapy Combinations Into the Clinic.推动免疫疗法联合方案进入临床应用。
Oncology (Williston Park). 2015 Dec;29(12):990-1002.
4
Extracellular matrix and the myeloid-in-myeloma compartment: balancing tolerogenic and immunogenic inflammation in the myeloma niche.细胞外基质与骨髓瘤中的髓系细胞区室：平衡骨髓瘤微环境中的致耐受性炎症和免疫原性炎症
J Leukoc Biol. 2017 Aug;102(2):265-275. doi: 10.1189/jlb.3MR1116-468R. Epub 2017 Mar 2.
5
Immune checkpoint pathways: perspectives on myeloid malignancies.免疫检查点通路：关于髓系恶性肿瘤的观点
Leuk Lymphoma. 2016 May;57(5):995-1001. doi: 10.3109/10428194.2015.1107554. Epub 2016 Feb 25.
6
Immune Checkpoint Molecules on Tumor-Infiltrating Lymphocytes and Their Association with Tertiary Lymphoid Structures in Human Breast Cancer.肿瘤浸润淋巴细胞上的免疫检查点分子及其与人乳腺癌中三级淋巴结构的关联
Front Immunol. 2017 Oct 30;8:1412. doi: 10.3389/fimmu.2017.01412. eCollection 2017.
7
The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.CD47-SIRPα信号轴作为癌症中的一种固有免疫检查点。
Immunol Rev. 2017 Mar;276(1):145-164. doi: 10.1111/imr.12527.
8
Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis.阿仑单抗治疗可改变多发性硬化症患者循环中的固有免疫细胞。
Neurol Neuroimmunol Neuroinflamm. 2016 Oct 12;3(6):e289. doi: 10.1212/NXI.0000000000000289. eCollection 2016 Dec.
9
Cytokine Networks between Innate Lymphoid Cells and Myeloid Cells.固有淋巴细胞和髓样细胞之间的细胞因子网络。
Front Immunol. 2018 Feb 7;9:191. doi: 10.3389/fimmu.2018.00191. eCollection 2018.
10
FAP positive fibroblasts induce immune checkpoint blockade resistance in colorectal cancer via promoting immunosuppression.FAP阳性成纤维细胞通过促进免疫抑制诱导结直肠癌对免疫检查点阻断产生抗性。
Biochem Biophys Res Commun. 2017 May 20;487(1):8-14. doi: 10.1016/j.bbrc.2017.03.039. Epub 2017 Mar 14.

引用本文的文献

1
Modulation of the immune microenvironment using nanomaterials: a new strategy for tumor immunotherapy.利用纳米材料调控免疫微环境：肿瘤免疫治疗的新策略。
Front Immunol. 2025 Jul 2;16:1614640. doi: 10.3389/fimmu.2025.1614640. eCollection 2025.
2
CyTOF as a suitable tool for stratification and monitoring of cancer patients.质谱流式细胞术作为一种适用于癌症患者分层和监测的工具。
J Transl Med. 2025 Jul 1;23(1):724. doi: 10.1186/s12967-025-06764-0.
3
In vivo labelling resolves distinct temporal, spatial, and functional properties of tumour macrophages, and identifies subset-specific effects of PD-L1 blockade.体内标记解析了肿瘤巨噬细胞不同的时间、空间和功能特性，并确定了程序性死亡受体配体1（PD-L1）阻断的亚群特异性效应。
Cancer Immunol Res. 2025 Jun 16. doi: 10.1158/2326-6066.CIR-24-1233.
4
Cold and hot tumors: from molecular mechanisms to targeted therapy.冷肿瘤和热肿瘤：从分子机制到靶向治疗。
Signal Transduct Target Ther. 2024 Oct 18;9(1):274. doi: 10.1038/s41392-024-01979-x.
5
Phenotyping Tumor Heterogeneity through Proteogenomics: Study Models and Challenges.通过蛋白质基因组学进行肿瘤异质性表型分析：研究模型与挑战。
Int J Mol Sci. 2024 Aug 14;25(16):8830. doi: 10.3390/ijms25168830.
6
Host-derived Interleukin 1α induces an immunosuppressive tumor microenvironment via regulating monocyte-to-macrophage differentiation.宿主来源的白细胞介素1α通过调节单核细胞向巨噬细胞的分化诱导免疫抑制性肿瘤微环境。
bioRxiv. 2024 May 5:2024.05.03.592354. doi: 10.1101/2024.05.03.592354.
7
Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18.通过靶向 USP18 介导的 NEDD4 降解 CSF1R 对肿瘤相关巨噬细胞进行重编程。
Cell Rep. 2023 Dec 26;42(12):113560. doi: 10.1016/j.celrep.2023.113560. Epub 2023 Dec 13.
8
Immunotherapy Enhancement by Targeting Extracellular Tumor pH in Triple-Negative Breast Cancer Mouse Model.通过靶向三阴性乳腺癌小鼠模型中的细胞外肿瘤pH值增强免疫疗法
Cancers (Basel). 2023 Oct 11;15(20):4931. doi: 10.3390/cancers15204931.
9
The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy.趋化因子 CX3CL1-CX3CR1 轴可促进肿瘤免疫逃逸，而新型 CX3CR1 单克隆抗体阻断该轴可增强抗 PD-1 免疫治疗的反应。
Front Immunol. 2023 Sep 13;14:1237715. doi: 10.3389/fimmu.2023.1237715. eCollection 2023.
10
Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti-PD-1 resistance.靶向 TREM1 通过抑制髓系来源的抑制细胞并抑制抗 PD-1 耐药性来增强抗肿瘤 T 细胞免疫。
J Clin Invest. 2023 Nov 1;133(21):e167951. doi: 10.1172/JCI167951.