Department of Surgical Oncology, Máxima Medical Center, Veldhoven, the Netherlands.
Department of Gastro-intestinal Surgery, Viecuri Medical Center, Venlo, the Netherlands.
Eur J Surg Oncol. 2019 Feb;45(2):174-179. doi: 10.1016/j.ejso.2018.11.001. Epub 2018 Nov 10.
Substantial progress has been made in the treatment of rectal cancer in the past two decades. Low anterior resection is a cornerstone in current treatment, combined with neo-adjuvant (chemo-) radiation in selected cases. However, side effects such as increased frequency, urgency and incontinence are seen in a majority of patients postoperatively. These symptoms, referred to as low anterior resection syndrome (LARS), have a severe impact on quality of life. Management of LARS is complex, and surgeons seem to underestimate and misinterpret the impact of symptoms associated with LARS.
We investigated the awareness and management of LARS in The Netherlands, conducting a national survey in which colorectal surgeons and colorectal care nurses were asked for their views on this complex syndrome.
242 health-care professionals participated in the survey. Most participants estimate the prevalence of major LARS is 20-40% after low anterior resection (LAR); a severe underestimation of actual prevalence - around 70%. Only 10% of surgeons use LARS screening tools in the preoperative period, and fewer than half of surgeons use LARS scores before or after a LAR. Although most surgeons inform their patients preoperatively about the changes in bowel function that they may experience after rectal cancer treatment, a majority of these surgeons indicate more information and patient counselling would improve the quality of life of their patients.
Impact and prevalence of LARS is underestimated by their physicians. Uniform clinical guidelines should be developed to guide physicians in adequate management of patients with LARS.
在过去的二十年中,直肠癌的治疗取得了重大进展。低位前切除术是当前治疗的基石,在某些情况下结合新辅助(化疗)放疗。然而,大多数患者术后会出现诸如频率增加、尿急和失禁等副作用。这些症状被称为低位前切除综合征(LARS),严重影响生活质量。LARS 的管理较为复杂,外科医生似乎低估并误解了与 LARS 相关症状的影响。
我们调查了荷兰对 LARS 的认识和管理情况,对结直肠外科医生和结直肠护理护士进行了一项全国性调查,了解他们对这种复杂综合征的看法。
242 名医疗保健专业人员参与了调查。大多数参与者估计低位前切除(LAR)后 LARS 的主要发生率为 20-40%;这严重低估了实际发生率 - 约为 70%。只有 10%的外科医生在术前使用 LARS 筛查工具,不到一半的外科医生在 LAR 前后使用 LARS 评分。尽管大多数外科医生在术前告知患者他们可能在直肠癌治疗后出现的肠道功能变化,但大多数外科医生表示,更多的信息和患者咨询将提高患者的生活质量。
LARS 的影响和流行率被医生低估了。应制定统一的临床指南,指导医生对 LARS 患者进行适当的管理。