Department of Digestive Surgery, Turku University Hospital, Kiinamyllynkatu 4-8, Turku, 20520, Finland.
Department of Digestive Surgery, Turku University Hospital, University of Turku, Turku, Finland.
Scand J Surg. 2021 Sep;110(3):414-419. doi: 10.1177/1457496920930142. Epub 2020 Jun 18.
Low anterior resection syndrome is common after anterior resection for rectal cancer. Its severity can be tested with the low anterior resection syndrome score. We have translated the low anterior resection syndrome score to Finnish, and the aim of this study is to validate the translation.
The translated Finnish low anterior resection syndrome score and European Organisation for Research and Treatment of Cancer quality-of-life questionnaire-C30 and QLQ-CR29 questionnaires were sent to 159 surviving patients operated with anterior resection for rectal adenocarcinoma between 2007 and 2014 in a tertiary referral center. Psychometric properties of the translation were evaluated in comparison to quality-of-life scales and in different risk factor groups.
In the study, 104 (65%) patients returned the questionnaires. Of these, 56 (54%) had major low anterior resection syndrome, 26 (25%) had minor low anterior resection syndrome, and 22 (21%) had no low anterior resection syndrome. Patients with major low anterior resection syndrome had a significantly lower quality of life and more defecatory symptoms as assessed with the European Organisation for Research and Treatment of Cancer questionnaires compared with those with no low anterior resection syndrome. Patients operated with total mesorectal excision had significantly higher low anterior resection syndrome scores compared with those operated with partial mesorectal excision (median/interquartile range 32/15 and 29/11, respectively, = 0.037). The test-retest validity of the translation was good with an intraclass correlation coefficient of 0.77 (95% confidence interval 0.51-0.90).
The Finnish low anterior resection syndrome score is a valid test in the assessment of postoperative bowel function and its impact on the quality of life. It can be implemented to use during regular follow-up visits of Finnish-speaking rectal cancer patients.
直肠癌前切除术术后常发生前切除综合征。其严重程度可通过前切除综合征评分进行测试。我们已将前切除综合征评分翻译为芬兰语，本研究旨在验证其翻译的准确性。
在一家三级转诊中心，我们向 2007 年至 2014 年间接受直肠腺癌前切除术的 159 例存活患者发送了芬兰语翻译的前切除综合征评分、欧洲癌症研究与治疗组织生活质量问卷-C30 和 QLQ-CR29 问卷。我们通过与生活质量量表的比较以及在不同风险因素组之间的比较，评估了翻译的心理测量特性。
在这项研究中，有 104 例（65%）患者返回了问卷。其中，56 例（54%）患者存在主要前切除综合征，26 例（25%）患者存在轻微前切除综合征，22 例（21%）患者不存在前切除综合征。与无前切除综合征的患者相比，患有主要前切除综合征的患者生活质量显著降低，排便症状更多，欧洲癌症研究与治疗组织问卷评估结果也显示如此。接受全直肠系膜切除术的患者前切除综合征评分明显高于接受部分直肠系膜切除术的患者（中位数/四分位间距分别为 32/15 和 29/11，P=0.037）。翻译的重测信度良好，组内相关系数为 0.77（95%置信区间为 0.51-0.90）。
芬兰语前切除综合征评分是评估术后肠道功能及其对生活质量影响的有效测试方法。该评分可用于芬兰语直肠肿瘤患者的常规随访。
