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“Risser+”分级:一种新的特发性脊柱侧凸骨骼成熟度分级系统。

The "Risser+" grade: a new grading system to classify skeletal maturity in idiopathic scoliosis.

机构信息

Boston Children Hospital, Harvard Medical School, Boston, USA.

Children's Mercy Hospital, Kansas City, USA.

出版信息

Eur Spine J. 2019 Mar;28(3):559-566. doi: 10.1007/s00586-018-5821-8. Epub 2018 Nov 16.

Abstract

PURPOSE

This study aims to propose and validate a new unified "Risser+" grade that combines the North American (NA) and European (EU) variants of the classic Risser score. The "Risser+ " grade can effectively combine the North American and European Risser Classifications for skeletal maturity with adequate intra-rater/inter-rater reliability and agreement.

METHODS

Agreement and reliability were evaluated for 6 raters (3-NA, 3-EU) who assessed 120 pelvic radiographs from the BrAIST trial, all female, average age 13.4 (range 10.1-16.5 years). Blinded raters reviewed x-rays at two time-points. Intra- and inter-rater agreement (RA) were established with Krippendorff's alpha (k-alpha), while intra- and inter-rater reliability (RR) were established with intraclass correlation coefficients (ICC). Acceptable agreement and reliability were set a priori at 0.80.

RESULTS

Inter-RA for the second reading met study requirements (k-alpha = 0.86 [0.81-0.90]) compared to the first reading (0.72 [0.63-0.79]) while combined readings was close to target agreement (0.79 [0.74-0.84]). Removal of 20 readings demonstrating outlier tendencies increased agreement for the first, second, and combined reads (k-alpha = 0.85, 0.89, 0.87, respectively). Intra-RA was sufficient for 4 out of 6 raters (k-alpha > 0.80) and one rater from EU and NA presented subpar intra-RA (k-alpha = 0.64 and 0.74, respectively). Inter-RR met study requirements overall reads (ICC = 0.96 [0.95-0.97]) including the first (0.94 [0.92-0.95]) and second (0.97 [0.97-0.98]) reads, independently.

CONCLUSIONS

The Risser+ system showed excellent reliability across multiple reads and raters and demonstrated 79% agreement overall reads and ratings. Agreement increased to over 85% when raters could distinguish Risser 0 + from Risser 5. These slides can be retrieved from electronic supplementary material.

摘要

目的

本研究旨在提出并验证一种新的统一的“Risser+”分级,该分级结合了北美(NA)和欧洲(EU)经典 Risser 评分的变体。“Risser+”分级可以有效地将北美和欧洲的骨骼成熟度 Risser 分级结合起来,具有足够的内部和外部评估者之间的可靠性和一致性。

方法

评估了 6 名评估者(3 名北美,3 名欧洲)对来自 BrAIST 试验的 120 张骨盆 X 光片的评估,所有女性,平均年龄 13.4 岁(范围 10.1-16.5 岁)。盲法评估者在两个时间点回顾 X 光片。内部和外部评估者之间的一致性(RA)通过 Krippendorff 的 alpha(k-alpha)来确定,而内部和外部评估者之间的可靠性(RR)通过组内相关系数(ICC)来确定。可接受的一致性和可靠性被设定为 0.80。

结果

与第一次阅读相比,第二次阅读的内部评估者之间的一致性(k-alpha=0.86 [0.81-0.90])达到了研究要求,而合并阅读则接近目标一致性(0.79 [0.74-0.84])。剔除 20 份显示出离群趋势的阅读数据后,第一次、第二次和合并阅读的一致性都有所提高(k-alpha=0.85、0.89、0.87)。有 4 名评估者的内部评估者之间的一致性是足够的(k-alpha>0.80),而来自欧洲和北美的一名评估者的内部评估者之间的一致性较差(k-alpha=0.64 和 0.74)。整体阅读的内部评估者之间的可靠性(ICC=0.96 [0.95-0.97])包括第一次(0.94 [0.92-0.95])和第二次(0.97 [0.97-0.98])阅读,均达到了研究要求。

结论

Risser+系统在多次阅读和评估者中表现出了极好的可靠性,并在整体阅读和评估中达到了 79%的一致性。当评估者能够区分 Risser 0+和 Risser 5 时,一致性增加到 85%以上。这些幻灯片可以从电子补充材料中检索。

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