世界卫生组织诊断标准在东地中海地区骨质疏松症的患病率：系统评价和荟萃分析。

Prevalence of osteoporosis with the World Health Organization diagnostic criteria in the Eastern Mediterranean Region: a systematic review and meta-analysis.

机构信息

Student Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

出版信息

Arch Osteoporos. 2018 Nov 17;13(1):129. doi: 10.1007/s11657-018-0540-7.

DOI:10.1007/s11657-018-0540-7

PMID:30448960

Abstract

UNLABELLED

A systematic review and meta-analysis was conducted on the prevalence of osteoporosis in the Eastern Mediterranean Region. The overall pooled prevalence of osteoporosis was 24.4%. The prevalence has increased significantly over the recent years. The highest pooled prevalence was in Saudi Arabia (32.7%), and the lowest was in Kuwait (15.1%).

PURPOSE

To conduct a systematic review and meta-analysis on the prevalence of osteoporosis in the Eastern Mediterranean Region (EMR), as defined by the World Health Organization.

METHODS

We included all observational studies reporting the prevalence of osteoporosis among general population. We searched literatures from the databases of PubMed, Scopus, Web of Science, and Index Medicus for the EMR published between January 2000 and December 2017 with no restriction of language. Two reviewers independently contributed in study selection and data extraction. STATA software was used for analyzing the collected data.

RESULTS

A total of 1692 citations were retrieved. After excluding the irrelevant articles, 36 eligible studies were included. The overall pooled prevalence rate of osteoporosis in the EMR on 31,593 participants was 24.4% (95% confidence interval [CI], 20.4-28.4). Based on femoral densitometry, the prevalence of osteoporosis was 16.8% (95% CI, 9.5-24.2), and based on spinal densitometry, it was 24.3% (95% CI, 19.4-29.2). The pooled prevalence in males was 20.5% (95% CI, 10.5-30.5), compared with 24.4% (95% CI, 20.2-28.6) in females. The prevalence rate was significantly higher in 2007-2015 (32.7%; 95% CI, 25.1-40.3) than in 2000-2006 (19.8%; 95% CI, 12.5-27).

CONCLUSIONS

Our findings indicate a considerable prevalence of osteoporosis among the people of the EMR. The prevalence has increased during recent years, showing that osteoporosis is becoming a critical health problem in this region. Prevention and control measures need to be implemented by health service authorities.

摘要

目的

按照世界卫生组织的定义，对东地中海地区（EMR）骨质疏松症的流行情况进行系统评价和荟萃分析。

方法

我们纳入了所有报告普通人群骨质疏松症患病率的观察性研究。我们从 PubMed、Scopus、Web of Science 和 Index Medicus 数据库中检索了 2000 年 1 月至 2017 年 12 月期间发表的 EMR 相关文献，无语言限制。两名审查员独立进行了研究选择和数据提取。使用 STATA 软件分析收集的数据。

结果

共检索到 1692 条引文。剔除不相关的文章后，纳入 36 项符合条件的研究。31593 名参与者中 EMR 骨质疏松症的总体汇总患病率为 24.4%（95%置信区间[CI]，20.4-28.4）。基于股骨骨密度，骨质疏松症的患病率为 16.8%（95%CI，9.5-24.2），基于脊柱骨密度，其患病率为 24.3%（95%CI，19.4-29.2）。男性的汇总患病率为 20.5%（95%CI，10.5-30.5），而女性为 24.4%（95%CI，20.2-28.6）。2007-2015 年（32.7%；95%CI，25.1-40.3）的患病率明显高于 2000-2006 年（19.8%；95%CI，12.5-27）。