Jin Seong, An Chi Hwan, Jeong Ho Yong, Choi Woohwa, Hong Sun-Won, Song Hoon Ki, Kim Hyun Sung, Lee Yun Kyung, Kang Hyo Jung, Ahn Dong-Young, Yang Hea-Eun
Department of Physical Medicine and Rehabilitation, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea.
Prosthetic and Orthotic Center, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea.
J Clin Med. 2024 Jul 10;13(14):4033. doi: 10.3390/jcm13144033.
This study aimed to evaluate bone mineral density (BMD) discordance and its implications in veterans with unilateral lower-limb amputation, emphasizing the need for comprehensive hip assessments. Data were collected from 84 male veterans, and BMD was measured using dual-energy X-ray absorptiometry (DXA) at the lumbar spine, intact hip, and amputated hip. The T-scores for the lumbar spine, intact hip, and amputated hip were -0.27 ± 1.69, -0.25 ± 1.20, and -1.07 ± 1.33, respectively. Osteoporosis and osteopenia were present in 19% and 34.6% of patients, respectively. Osteopenia and osteoporosis were most prevalent in the hips on the amputated side (32.1% and 13.1%, respectively), followed by the lumbar spines (22.6% and 8.3%) and the hips on the intact side (17.9% and 2.4%). BMD discordance between the lumbar spine and hip was found in 47.6% of participants, while discordance between both hips was observed in 39.3%. Transfemoral amputees had significantly lower BMD at the amputated hip compared to transtibial amputees (-2.38 ± 1.72 vs. -0.87 ± 1.16, < 0.001). Veterans with unilateral lower-limb amputation exhibit a high prevalence of osteoporosis and significant BMD discordance, particularly between both hips. These findings underscore the necessity for bilateral hip assessments to ensure the accurate diagnosis and effective management of osteoporosis in this population.
本研究旨在评估单侧下肢截肢退伍军人的骨密度(BMD)不一致情况及其影响,强调全面髋部评估的必要性。收集了84名男性退伍军人的数据,并使用双能X线吸收法(DXA)测量腰椎、健侧髋部和截肢侧髋部的骨密度。腰椎、健侧髋部和截肢侧髋部的T值分别为-0.27±1.69、-0.25±1.20和-1.07±1.33。骨质疏松症和骨质减少症分别在19%和34.6%的患者中存在。骨质减少症和骨质疏松症在截肢侧髋部最为普遍(分别为32.1%和13.1%),其次是腰椎(22.6%和8.3%)和健侧髋部(17.9%和2.4%)。47.6%的参与者腰椎和髋部之间存在骨密度不一致,而两侧髋部之间的不一致率为39.3%。与经胫截肢者相比,经股截肢者截肢侧髋部的骨密度显著更低(-2.38±1.72 vs. -0.87±1.16,<0.001)。单侧下肢截肢退伍军人中骨质疏松症的患病率较高,且骨密度存在显著不一致,尤其是两侧髋部之间。这些发现强调了双侧髋部评估对于确保该人群骨质疏松症准确诊断和有效管理的必要性。