Matsuda Shogo, Nishikata Makoto, Takai Koji, Motoyoshi Takayuki, Yamashita Yasuhide, Kirishima Toshihiko, Yoshinami Naomi, Shintani Hiroyuki
Department of Gastroenterology, Keiju Medical Center, Japan.
Department of Gastroenterology, Kyoto City Hospital, Japan.
Intern Med. 2019 Mar 15;58(6):803-807. doi: 10.2169/internalmedicine.1805-18. Epub 2018 Nov 19.
We present an extremely rare case of amyloid A (AA) deposition in the gallbladder and review the literature on similar cases. The patient was a 76-year-old man who had been diagnosed with mild bronchiectasis three years previously, who was admitted to the hospital with right upper quadrant pain and fever. Computed tomography revealed swelling and wall thickening of the gallbladder with a small gallstone. The patient was diagnosed with acute cholecystitis and cholelithiasis and underwent open cholecystectomy. A postoperative histological examination revealed extensive AA deposition in the gallbladder wall. Thus, the definitive diagnosis was acute cholecystitis with AA amyloidosis.
我们报告了一例极为罕见的胆囊中淀粉样蛋白A(AA)沉积病例,并回顾了有关类似病例的文献。患者为一名76岁男性,三年前被诊断为轻度支气管扩张,因右上腹疼痛和发热入院。计算机断层扫描显示胆囊肿胀、壁增厚,伴有一枚小胆结石。患者被诊断为急性胆囊炎和胆石症,并接受了开腹胆囊切除术。术后组织学检查显示胆囊壁有广泛的AA沉积。因此,最终诊断为伴有AA淀粉样变性的急性胆囊炎。