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山奈酚和没食子酸对多种癌细胞系的细胞毒性比较活性。

Comparative cytotoxic activity between kaempferol and gallic acid against various cancer cell lines.

作者信息

Pham Hong Ngoc Thuy, Sakoff Jennette A, Vuong Quan Van, Bowyer Michael C, Scarlett Christopher J

机构信息

School of Environmental and Life Sciences, Faculty of Science, University of Newcastle, Ourimbah, NSW 2258, Australia.

Faculty of Food Technology, Nha Trang University, No. 2 Nguyen Dinh Chieu Street, Nha Trang City, Khanh Hoa, Vietnam.

出版信息

Data Brief. 2018 Oct 27;21:1033-1036. doi: 10.1016/j.dib.2018.10.121. eCollection 2018 Dec.

DOI:10.1016/j.dib.2018.10.121
PMID:30450396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6226582/
Abstract

This data article indicates the cytotoxicity of kaempferol and gallic acid across different cancer cell lines including A2780 (ovarian), H460 (lung), A431 (skin), MIA PaCa-2 (pancreas), Du145 (prostate), HT29 (colon), MCF-7 (breast), BE2-C (neuroblastoma), SJ-G2, U87 and SMA (glioblastoma). The dataset showed that the inhibitory activity of kaempferol was comparatively stronger than gallic acid. Thereby, kaempferol is offered as a potent anticancer agent for further investigation and beneficial as a dietary supplement. The data within this article relates to the research article entitled "Screening phytochemical content, antioxidant, antimicrobial and cytotoxic activities of (L.) G. Don stem extract and its fractions" (Pham et al., 2018).

摘要

本数据文章表明了山奈酚和没食子酸对不同癌细胞系的细胞毒性,这些癌细胞系包括A2780(卵巢癌)、H460(肺癌)、A431(皮肤癌)、MIA PaCa-2(胰腺癌)、Du145(前列腺癌)、HT29(结肠癌)、MCF-7(乳腺癌)、BE2-C(神经母细胞瘤)、SJ-G2、U87和SMA(胶质母细胞瘤)。数据集显示,山奈酚的抑制活性比没食子酸相对更强。因此,山奈酚作为一种有效的抗癌剂有待进一步研究,并且作为膳食补充剂是有益的。本文中的数据与题为“(L.) G. Don茎提取物及其馏分的植物化学成分筛选、抗氧化、抗菌和细胞毒性活性”的研究文章(Pham等人,2018年)相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c77/6226582/121e0300ae83/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c77/6226582/2175c064d6ee/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c77/6226582/121e0300ae83/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c77/6226582/2175c064d6ee/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c77/6226582/121e0300ae83/gr2.jpg

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