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惊恐障碍患者的输液前焦虑和实验室诱发的惊恐发作

Preinfusion anxiety and laboratory-induced panic attacks in panic disorder patients.

作者信息

Yeragani V K, Rainey J M, Pohl R, Balon R, Berchou R, Jolly S, Lycaki H

机构信息

Department of Psychiatry, Wayne State University School of Medicine, Detroit, MI.

出版信息

J Clin Psychiatry. 1988 Aug;49(8):302-6.

PMID:3045100
Abstract

Seventy panic disorder patients participated in a double-blind, placebo-controlled, randomized infusion study in which sodium lactate and isoproterenol were used to induce panic anxiety. Patients who panicked during lactate, isoproterenol, and placebo infusions generally had higher preinfusion anxiety scores. These findings held true irrespective of the order the infusions were given. Stepwise multiple regression analyses comparing panickers with nonpanickers as the criterion variable revealed that the items "afraid of going crazy," "feeling unsteady," and "feeling paralyzed" on the Panic Description Scale had the highest predicting values.

摘要

70名惊恐障碍患者参与了一项双盲、安慰剂对照、随机输注研究,其中使用乳酸钠和异丙肾上腺素诱发惊恐焦虑。在输注乳酸盐、异丙肾上腺素和安慰剂过程中出现惊恐的患者,其输注前焦虑评分通常更高。无论输注顺序如何,这些发现均成立。以惊恐者与非惊恐者作为标准变量进行的逐步多元回归分析显示,惊恐描述量表上的“害怕发疯”“感觉不稳”和“感觉麻痹”项目具有最高的预测价值。

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