a Department of Orthopedic Surgery and Trauma , Máxima Medical Center , Eindhoven ;
b Department of Epidemiology and Biostatistics , VU University Medical Center, Amsterdam Public Health (APH) Research Institute , Amsterdam.
Acta Orthop. 2019 Feb;90(1):15-20. doi: 10.1080/17453674.2018.1539567. Epub 2018 Nov 19.
Background and purpose - Improvement of physical function is one of the main treatment goals in severe hip osteoarthritis (OA) patients. The Osteoarthritis Research Society International (OARSI) has identified a core set of performance-based tests to assess the construct physical function: 30-s chair stand test (30-s CST), 4x10-meter fast-paced walk test (40 m FPWT), and a stair-climb test. Despite this recommendation, available evidence on the measurement properties is limited. We evaluated the reliability, validity, and responsiveness of these performance-based measures in patients with hip OA scheduled for total hip arthroplasty (THA). Patients and methods - Baseline and 12-month follow-up measurements were prospectively obtained in 90 end-stage hip OA patients who underwent THA. As there is no gold standard for comparison, the hypothesis testing method was used for construct validity and responsiveness analysis. A test can be assumed valid if ≥75% of predefined hypotheses are confirmed. A subgroup (n = 30) underwent test-retest measurements for reliability analysis. The Oxford Hip Score, Hip injury and Osteoarthritis Outcome Score-Physical Function Short Form, pain during activity score, and muscle strength were used as comparator instruments. Results - Test-retest reliability was appropriate; intraclass correlation coefficient values exceeded 0.70 for all 3 tests. None of the performance-based measures reached 75% hypothesis confirmation for the construct validity or responsiveness analysis. Interpretation - The performance-based tests have good reliability in the assessment of physical function. Construct validity and responsiveness, using patient-reported measures and muscle strength as comparator instruments, could not be confirmed. Therefore, our findings do not justify their use for clinical practice.
背景与目的-改善身体功能是严重髋关节炎(OA)患者的主要治疗目标之一。国际骨关节炎研究协会(OARSI)确定了一组核心的基于表现的测试来评估结构身体功能:30 秒椅站测试(30-s CST)、4x10 米快步走测试(40 m FPWT)和爬楼梯测试。尽管有此建议,但可用的测量特性证据有限。我们评估了这些基于表现的测量方法在计划接受全髋关节置换术(THA)的髋关节炎患者中的可靠性、有效性和反应性。
患者和方法-前瞻性地获得了 90 例接受 THA 的终末期髋关节炎患者的基线和 12 个月随访测量值。由于没有金标准进行比较,因此使用假设检验方法进行结构有效性和反应性分析。如果≥75%的预设假设得到证实,则可以假设测试有效。一个亚组(n=30)进行了测试-重测测量以进行可靠性分析。牛津髋关节评分、髋关节损伤和骨关节炎结果评分-物理功能简明量表、活动时疼痛评分和肌肉力量被用作比较仪器。
结果-测试-重测可靠性良好;所有 3 项测试的组内相关系数值均超过 0.70。在结构有效性或反应性分析中,没有任何基于表现的测量方法达到 75%的假设确认率。
解释-基于表现的测试在评估身体功能方面具有良好的可靠性。使用患者报告的测量值和肌肉力量作为比较仪器,结构有效性和反应性无法得到证实。因此,我们的研究结果不能证明其在临床实践中的应用是合理的。