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固体食物引入与食物过敏发展。

Solid Food Introduction and the Development of Food Allergies.

机构信息

Clinica Pediatrica Unit, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.

Pediatria, Azienda Ospedaliera di Imola, Via Montericco 4, 40026 Imola, Italy.

出版信息

Nutrients. 2018 Nov 17;10(11):1790. doi: 10.3390/nu10111790.

Abstract

The rise of food allergy in childhood, particularly among developed countries, has a significant weight on public health and involves serious implications for patients' quality of life. Even if the mechanisms of food tolerance and the complex interactions between the immune system and environmental factors are still mainly unknown, pediatricians have worldwide implemented preventive measures against allergic diseases. In the last few decades, the prevention of food allergy has tracked various strategies of complementary feeding with a modification of international guidelines from delayed introduction to early weaning. Current evidence shows that complementary foods, including allergenic ones, should be introduced into diet after four months, or even better, following World Health Organization advice, around six months irrespective of risk for allergy of the individual. The introduction of peanut is recommended before 12 months of age among infants affected by severe eczema and/or egg allergy to diminish the occurrence of peanut allergy in countries with high peanut consumption. The introduction of heated egg at 6⁻8 months of age may reduce egg allergy. Infants at high risk of allergy similarly to healthy children should introduce complementary foods taking into account family and cultural preferences.

摘要

儿童食物过敏的上升,尤其是在发达国家,对公共卫生有重大影响,并且对患者的生活质量有严重影响。即使食物耐受的机制和免疫系统与环境因素之间的复杂相互作用仍主要未知,但儿科医生已在全球范围内实施了预防过敏疾病的措施。在过去几十年中,食物过敏预防已跟踪了各种补充喂养策略,国际指南也随之从延迟引入改为早期断奶。目前的证据表明,补充食物,包括致敏食物,应在四个月后,甚至更好的是,按照世界卫生组织的建议,在六个月左右,无论个体的过敏风险如何,都应引入饮食。在高花生食用国家,建议将花生引入严重特应性皮炎和/或鸡蛋过敏的婴儿饮食中,以减少花生过敏的发生。在 6-8 个月大时引入加热鸡蛋可能会减少鸡蛋过敏。有过敏高风险的婴儿与健康儿童一样,应根据家庭和文化偏好引入补充食物。

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